Developmental Program

该计划一直是SPORE的一个主要重点，因为它提供了创新思想和活动的持续流动，以刺激SPORE翻译研究背景下的调查。发展研究计划提供了一种应对新机遇的手段，旨在鼓励和促进新的研究工作。该计划利用约翰霍普金斯大学和外部调查人员的广泛专业知识，为有潜力发展成为成熟的转化研究途径，合作和新方法的试点项目提供资金，以融入其他研究项目。在过去的几年里，癌症中心已经增加了资金提供给我们的每个试点项目受助人约50%每个奖项（平均）。在过去的两年中，肿瘤中心内GI癌症项目的形成也为其他基础和临床试点项目提供了支持，这些项目不打算像SPORE发展项目的目标那样具有转化性。今年，我们还获得了每年由机构来源资助的另外两个胰腺癌试点项目的承诺。这些资源，以及拟议的SPORE资助期间总预算减少所带来的资金压力，使我们能够将一些财政来源从SPORE转移到该机构，正如新提出的发展研究预算所反映的那样。

The Program has been a major focus of the SPORE because it provides for a continuous flow of innovative ideas and activity to stimulate investigation in the context of SPORE translational research. The Developmental Research Program provides a means to respond to new opportunities, and is designed to encourage and facilitate new research efforts. The Program takes advantage of the broad expertise of researchers at The Johns Hopkins University and of external investigators by providing funds for pilot projects with potential for development into full-fledged translational research avenues, collaborations, and new methodologies for integration into other Research Projects. In most prior years, the Cancer Center has augmented the funding provided to each of our pilot project recipients by approximately 50% per award (on average). In the past two years, the formation of a GI Cancer program within the Oncology Center has also provided support for additional basic and clinical pilot projects that are not intended to be as translational as the goals of the SPORE Developmental Projects. Within this year, we also have gained a commitment for an additional two pancreatic cancer pilot projects to be funded by institutional sources each year. These resources, and funding pressures from a reduced overall budget for the proposed SPORE funding period, have allowed us to shift some of the financial sources from the SPORE to the institution, as reflected in the newly proposed Developmental Research Budget.