Developmental Program

该计划一直是SPORE的主要焦点，因为它提供了创新思想和活动的持续流动，以刺激SPORE转化研究背景下的调查。发展研究计划提供了一种应对新机遇的手段，旨在鼓励和促进新的研究工作。该计划利用约翰霍普金斯大学研究人员和外部研究人员的广泛专业知识，为试点项目提供资金，这些项目有可能发展成为成熟的转化研究途径、合作和整合其他研究项目的新方法。在过去的几年里，癌症中心为每个试点项目接受者增加了大约50%的资金（平均）。在过去的两年中，肿瘤中心内GI癌症项目的形成也为额外的基础和临床试点项目提供了支持，这些项目并不打算像孢子发展项目那样具有转化性。在今年内，我们亦获承诺每年增加两项由机构资助的胰腺癌试验计划。这些资源，以及来自《孢子》资助期整体预算减少的资金压力，使我们能够将一些资金来源从《孢子》转移到机构，正如新提议的发展研究预算所反映的那样。

The Program has been a major focus of the SPORE because it provides for a continuous flow of innovative ideas and activity to stimulate investigation in the context of SPORE translational research. The Developmental Research Program provides a means to respond to new opportunities, and is designed to encourage and facilitate new research efforts. The Program takes advantage of the broad expertise of researchers at The Johns Hopkins University and of external investigators by providing funds for pilot projects with potential for development into full-fledged translational research avenues, collaborations, and new methodologies for integration into other Research Projects. In most prior years, the Cancer Center has augmented the funding provided to each of our pilot project recipients by approximately 50% per award (on average). In the past two years, the formation of a GI Cancer program within the Oncology Center has also provided support for additional basic and clinical pilot projects that are not intended to be as translational as the goals of the SPORE Developmental Projects. Within this year, we also have gained a commitment for an additional two pancreatic cancer pilot projects to be funded by institutional sources each year. These resources, and funding pressures from a reduced overall budget for the proposed SPORE funding period, have allowed us to shift some of the financial sources from the SPORE to the institution, as reflected in the newly proposed Developmental Research Budget.