NINDS Network for Excellence in Neuroscience: Clinical Research Site at UC Davis

描述（由申请人提供）：我们的目标是成为由国家神经疾病和中风研究所（NINDS）建立的神经科学临床试验卓越网络（NEXT）的参与临床研究中心。加州大学戴维斯分校的NEXT临床研究中心将：1）通过组装一个 加州大学戴维斯分校附属神经学家、神经外科医生、理疗师和其他专家的区域网络，目前参与各种神经系统疾病的临床试验（神经肌肉疾病、运动障碍、共济失调、神经发育障碍、成人痴呆、脑损伤、多发性硬化、中风、神经性疼痛和癫痫发作）; 2）利用加州大学戴维斯分校临床培训科学中心的现有研究资源，在临床试验的开发和实施中建立现有的合作关系并建立新的合作关系，3）提供当地和区域社区外展服务，以改善北方加州不同人群的患者招募和保留;以及4）为年轻的研究人员提供临床研究培训和支持性环境，以培养更多的研究技能，并帮助他们晋升到更高的职位。一个经验丰富和有竞争力的更新CTSC，在神经科学的专家临床试验组，和创新的临床研究影响临床试验的组合，理想的位置加州大学戴维斯分校成为卓越的临床神经科学临床试验网络（NEXT网站）的杰出临床研究网站。我们的总体目标是在NINDS NEXT与行业，学术界和/或基金会之间的合作伙伴关系中，在7年内对儿童和成人神经系统疾病进行5至7项多中心临床试验。

DESCRIPTION (provided by applicant): Our objective is to become a participating Clinical Research Site in the Network for Excellence in Neuroscience Clinical Trials (NEXT) that is being established by the National Institute of Neurological Disorders and Stroke (NINDS). The NEXT Clinical Research site at UC Davis will: 1) facilitate high-quality clinical trials by assembling a regional network of UC Davis-affiliated neurologists, neurosurgeons, physiatrists and other specialists that are currently involved in conducting clinical trials in a wide variety of neurologcal disorders (neuromuscular disorders, movement disorders, ataxias, neurodevelopmental disorders, adult dementias, brain injury, multiple sclerosis, stroke, neuropathic pain, and epileptic seizures) in adults or children; 2) leverage existing research resources from the UC Davis Clinical Training Science Center to build on existing and create new collaborations between in the development and conduct of clinical trials, 3) provide local and regional community outreach to improve patient recruitment and retention from diverse populations across Northern California; and 4) provide clinical-research training and a supportive environment for young investigators to develop additional research skills and to assist them in progressing to more senior status. The combination of an experienced and competitively renewed CTSC, an expert clinical trials group in the neurosciences, and innovative clinical research impacting clinical trials, ideally positions UC Davis to be an outstanding Clinical Research Site for the Network of Excellence in Clinical Neuroscience Clinical Trials (NEXT site). Our overall goal is to conduct 5 to 7 multicenter clinical trials over 7 years in childhood and adut neurologic diseases developed in partnerships between the NINDS NEXT and industry, academia, and/or foundations.