NINDS Network for Excellence in Neuroscience: Clinical Research Site at UC Davis

NINDS 神经科学卓越网络：加州大学戴维斯分校的临床研究中心

• 批准号: 8720074
• 负责人: Craig M. McDonald
• 金额: $ 24.05万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720074
• 关键词: Academia; Academy; Adult; Advocacy; Affect; Agreement; Ataxia; Award; Biological Markers; Brain Injuries; California; Caring; Center for Translational Science Activities; Child; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Cooperative Group; Collaborations; Communities; Community Outreach; Conceptions; Conduct Clinical Trials; Dementia; Development; Disease; Duchenne muscular dystrophy; Education; Environment; Epilepsy; FXTAS; Faculty; Foundations; Fragile X Syndrome; Goals; Health; Health system; Industry; Institutional Review Boards; Leadership; Mentors; Movement Disorders; Multiple Sclerosis; National Institute of Neurological Disorders and Stroke; Neurodevelopmental Disability; Neurodevelopmental Disorder; Neurologic; Neurologist; Neuromuscular Diseases; Neurosciences; Neurosurgeon; Outcome; Patient Recruitments; Patients; Phase II Clinical Trials; Physicians; Population; Population Heterogeneity; Positioning Attribute; Preparation; Protocols documentation; Quality of life; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Science; Sclerosis; Site; Specialist; Stroke; Structure; Therapy Clinical Trials; Training; Training Programs; Translational Research; Tremor/Ataxia Syndrome; Universities; Work; burden of illness; clinical research site; design; experience; improved; innovation; medical schools; member; multidisciplinary; nervous system disorder; neuroimaging; novel; novel therapeutics; outreach; painful neuropathy; research facility; skills

DESCRIPTION (provided by applicant): Our objective is to become a participating Clinical Research Site in the Network for Excellence in Neuroscience Clinical Trials (NEXT) that is being established by the National Institute of Neurological Disorders and Stroke (NINDS). The NEXT Clinical Research site at UC Davis will: 1) facilitate high-quality clinical trials by assembling a regional network of UC Davis-affiliated neurologists, neurosurgeons, physiatrists and other specialists that are currently involved in conducting clinical trials in a wide variety of neurologcal disorders (neuromuscular disorders, movement disorders, ataxias, neurodevelopmental disorders, adult dementias, brain injury, multiple sclerosis, stroke, neuropathic pain, and epileptic seizures) in adults or children; 2) leverage existing research resources from the UC Davis Clinical Training Science Center to build on existing and create new collaborations between in the development and conduct of clinical trials, 3) provide local and regional community outreach to improve patient recruitment and retention from diverse populations across Northern California; and 4) provide clinical-research training and a supportive environment for young investigators to develop additional research skills and to assist them in progressing to more senior status. The combination of an experienced and competitively renewed CTSC, an expert clinical trials group in the neurosciences, and innovative clinical research impacting clinical trials, ideally positions UC Davis to be an outstanding Clinical Research Site for the Network of Excellence in Clinical Neuroscience Clinical Trials (NEXT site). Our overall goal is to conduct 5 to 7 multicenter clinical trials over 7 years in childhood and adut neurologic diseases developed in partnerships between the NINDS NEXT and industry, academia, and/or foundations.

描述(由申请者提供)：我们的目标是成为由国家神经疾病和中风研究所(NINDS)建立的神经科学临床试验卓越网络(NEXT)中的一个参与临床研究网站。加州大学戴维斯分校的下一个临床研究地点将：1)通过组装一个 加州大学戴维斯分校附属神经学家、神经外科医生、理疗师和其他专家组成的区域网络，目前参与成人或儿童的各种神经疾病(神经肌肉障碍、运动障碍、共济失调、神经发育障碍、成人痴呆、脑损伤、多发性硬化症、中风、神经病理性疼痛和癫痫发作)的临床试验；2)利用加州大学戴维斯分校临床培训科学中心的现有研究资源，在临床试验的开发和实施方面建立现有的合作关系，3)提供当地和地区社区宣传，以改善整个北加州不同人群中的患者招募和留住；以及4)为年轻研究人员提供临床研究培训和支持性环境，以发展更多的研究技能，并帮助他们晋升到更高的地位。经验丰富且更新极具竞争力的CTSC是神经科学领域的专家临床试验团队，与影响临床试验的创新临床研究相结合，使加州大学戴维斯分校成为卓越临床神经科学临床试验网络(NEXT SITE)的杰出临床研究站点。我们的总体目标是在7年内进行5至7个多中心儿童临床试验，以及NINDS NEXT与工业界、学术界和/或基金会合作开发的ADUT神经系统疾病。