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Protein Chemistry Core

Protein Chemistry Core
蛋白质化学核心
批准号：
8554109
负责人：
Deborah Morrison
金额：
$17.54万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8554109
关键词：
AcetylationAmino Acid SequenceAmino AcidsBuffersCCRChargeCommunitiesComputer softwareDigestionDimensionsExtramural ActivitiesGelHigh Pressure Liquid ChromatographyImmunoblottingInstitutesIntramural ResearchIsoelectric FocusingLabelLaboratoriesLiquid substanceMapsMass Spectrum AnalysisMethodsMethylationModificationMolecular WeightPeptide MappingPeptide Sequence DeterminationPeptidesPhasePhosphoamino AcidsPhosphorylationPhosphorylation SitePositioning AttributePost-Translational Protein ProcessingProcessProtein ChemistryProteinsProteomicsRadioactiveRadioactive SequencingResearch PersonnelResourcesSamplingSerineServicesSiteStaining methodStainsTechniquesTechnologyThreonineTyrosineUnited States National Institutes of Healthcomparativedrug modificationinterestpressureprotein aminoacid sequencetwo-dimensional

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英文摘要
During 2011-2012, the Protein Chemistry Core provided services to investigators in the NCI-CCR as well as other NIH institutes. In addition, the Protein Chemistry Core collaborated with laboratories in the extramural community. The Core performed endoproteolytic digestions on 32-P labeled protein samples and analyzed the resulting peptides by high pressure liquid chomatography, phosphoamino acid analysis and Edman degredation, resulting in the identification of sites of protein phosphorylation. The Core also processed samples for comparative 2D-gel analysis and served as a resource to investigators regarding these techniques.
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Regulation of Ras-Dependent Signal Transduction Pathways
  • 批准号：
    8937711
  • 项目类别：
  • 资助金额：
    $60.81万
  • 财政年份：
    --
  • 负责人：
    Deborah Morrison
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Role of Protein Scaffolds in RTK-Ras-dependent Signal Transduction
  • 批准号：
    9343799
  • 项目类别：
  • 资助金额：
    $60.29万
  • 财政年份：
    --
  • 负责人：
    Deborah Morrison
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Role of Protein Scaffolds in RTKRas-dependent Signal Transduction
  • 批准号：
    9153776
  • 项目类别：
  • 资助金额：
    $66.94万
  • 财政年份：
    --
  • 负责人：
    Deborah Morrison
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
Regulation of Ras-Dependent Signal Transduction Pathways
  • 批准号：
    8552667
  • 项目类别：
  • 资助金额：
    $64.31万
  • 财政年份：
    --
  • 负责人：
    Deborah Morrison
  • 依托单位：
    DIVISION OF BASIC SCIENCES - NCI
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