Research Training Program in Molecular and Cellular Hematology

分子和细胞血液学研究培训计划

• 批准号: 8320212
• 负责人: Margaret H Baron
• 金额: $ 24.64万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8320212
• 关键词: Hematology; Molecular; Research Training; Training Programs

The objective of this new proposal is to use an interactive, collaborative, multidisciplinary approach to train talented young physician-scientists (MD and MD PhD) or PhD scientists for a successful career in investigative hematology research. The rationale for developing this program is our belief that Mount Sinai School of Medicine offers diverse scientific opportunities in an outstanding research environment, that we have a faculty that is dedicated to training scientists and physician-scientists for a career in academic hematology, stem cell biology, and regenerative medicine, and that we wish to have an impact on the education of future investigative hematologists. Faculty have been integrated into this program from various departments and institutes and from the Rockefeller University. Candidates for this training grant will be expected to devote a minimum of two years to training in basic or translational hematology. The trainees will select a mentor from one of the eight broad areas encompassed by this program: normal and malignant hematopoiesis, developmental hematopoiesis, adult and embryonic stem cell research, analysis of signaling pathways in hematologic processes, cell adhesion and migration within hematopoietic tissues and the vasculature, normal coagulation and inherited clotting disorders, immune cell development and function, and cell and gene therapy and transplantation. Throughout the training period, trainees will devote at least 90% of their time to research. Trainees will focus on an individualized research project under the guidance of one or more faculty preceptors. In addition, they will participate in weekly laboratory meetings, spend a portion of their time attending specific divisional, departmental and institutional research-oriented conferences, and will enroll in didactic, graduate level courses during the first and second years of training. Along with the enormous growth in the research portfolio of the Division of Hematology and Medical Oncology and the recruitment of new faculty over the past decade, we are now in a very strong position to provide an exceptional training opportunity that should be a magnet for the many outstanding trainees who wish to pursue a career in academic hematology research in New York City. cRELEVANCE (See instructions): A T32 award is essential for us to develop a training program that is commensurate with the high caliber of our faculty. The proposed training program will expand the pool of well-trained researchers in molecular and cellular hematology by extending the existing research training opportunities at this institution and will help produce some of the future leaders in hematology and stem cell biology research.

这项新提案的目标是使用互动、协作、多学科的方法来培训 有才华的年轻医师科学家（医学博士和医学博士）或博士科学家在以下领域取得成功的职业生涯 血液学研究。开发该计划的理由是我们相信西奈山 医学院在出色的研究环境中提供多样化的科学机会，我们 拥有一支致力于培训科学家和医师科学家从事学术职业的教师队伍 血液学、干细胞生物学和再生医学，我们希望对 未来研究血液学家的教育。来自不同领域的教师已融入该计划 部门和研究所以及洛克菲勒大学。该培训补助金的候选人将是 预计将至少投入两年时间进行基础或转化血液学培训。学员们将 从该计划涵盖的八个广泛领域之一中选择一位导师：正常和恶性 造血、发育造血、成体和胚胎干细胞研究、信号分析 血液学过程、造血组织内细胞粘附和迁移的途径以及 脉管系统、正常凝血和遗传性凝血障碍、免疫细胞发育和功能，以及 细胞和基因治疗以及移植。整个培训期间，学员投入至少90% 他们的研究时间。学员将在一位导师的指导下专注于个性化的研究项目 或更多教师导师。此外，他们还将参加每周一次的实验室会议，花费一部分时间 他们参加特定部门、部门和机构研究型会议的时间，并将 在培训的第一年和第二年报名参加研究生水平的教学课程。随着 血液学和肿瘤内科研究组合的巨大增长以及 在过去十年中招聘了新教师，我们现在处于非常有利的地位，可以提供 难得的培训机会，应该会吸引许多希望成为优秀学员的人 在纽约市从事学术血液学研究。 相关性（参见说明）： T32 奖项对于我们制定与高素质人才相称的培训计划至关重要 我们的教师。拟议的培训计划将扩大分子和分子生物学领域训练有素的研究人员队伍 通过扩展该机构现有的研究培训机会，细胞血液学将有助于 培养血液学和干细胞生物学研究领域的一些未来领导者。