Research Training Program in Molecular and Cellular Hematology

描述(由申请人提供)： 这项新建议的目标是使用互动、协作、多学科的方法来培养有才华的年轻内科科学家(医学博士和医学博士)或博士科学家，以便在血液学研究领域取得成功。开发这一项目的理由是我们相信，西奈山医学院在出色的研究环境中提供了多样化的科学机会，我们拥有一支致力于培养科学家和内科科学家从事学术血液学、干细胞生物学和再生医学事业的教职员工，我们希望对未来研究血液学家的教育产生影响。来自不同部门和研究所以及洛克菲勒大学的教职员工都被整合到这个项目中。这项培训补助金的申请者将至少投入两年时间进行基础血液学或转化性血液学方面的培训。学员将从该计划涵盖的八个广泛领域中选择一位导师：正常和恶性造血、发育中的造血、成人和胚胎干细胞研究、血液过程中的信号通路分析、造血组织和血管内的细胞黏附和迁移、正常凝血和遗传性凝血障碍、免疫细胞的发展和功能，以及细胞和基因治疗和移植。在整个培训期间，学员将至少90%的时间用于研究。受训者将在一名或多名教员的指导下专注于个性化的研究项目。此外，他们将参加每周一次的实验室会议，花一部分时间参加特定的部门、部门和机构研究会议，并将在第一年和第二年的培训期间参加教学、研究生水平的课程。随着过去十年来血液病和内科肿瘤科研究组合的巨大增长和新教师的招聘，我们现在处于非常有利的地位，可以提供一个特殊的培训机会，应该会吸引许多希望在纽约市从事血液学学术研究的优秀学员。

DESCRIPTION (provided by applicant): The objective of this new proposal is to use an interactive, collaborative, multidisciplinary approach to train talented young physician-scientists (MD and MD PhD) or PhD scientists for a successful career in investigative hematology research. The rationale for developing this program is our belief that Mount Sinai School of Medicine offers diverse scientific opportunities in an outstanding research environment, that we have a faculty that is dedicated to training scientists and physician-scientists for a career in academic hematology, stem cell biology, and regenerative medicine, and that we wish to have an impact on the education of future investigative hematologists. Faculty has been integrated into this program from various departments and institutes and from the Rockefeller University. Candidates for this training grant will be expected to devote a minimum of two years to training in basic or translational hematology. The trainees will select a mentor from one of the eight broad areas encompassed by this program: normal and malignant hematopoiesis, developmental hematopoiesis, adult and embryonic stem cell research, analysis of signaling pathways in hematologic processes, cell adhesion and migration within hematopoietic tissues and the vasculature, normal coagulation and inherited clotting disorders, immune cell development and function, and cell and gene therapy and transplantation. Throughout the training period, trainees will devote at least 90% of their time to research. Trainees will focus on an individualized research project under the guidance of one or more faculty preceptors. In addition, they will participate in weekly laboratory meetings, spend a portion of their time attending specific divisional, departmental and institutional research-oriented conferences, and will enroll in didactic, graduate level courses during the first and second years of training. Along with the enormous growth in the research portfolio of the Division of Hematology and Medical Oncology and the recruitment of new faculty over the past decade, we are now in a very strong position to provide an exceptional training opportunity that should be a magnet for the many outstanding trainees who wish to pursue a career in academic hematology research in New York City.