PillStream: Agile High-Throughput Assembly of Custom Multi-Medication Packaging

PillStream:定制多种药物包装的敏捷高通量组装

基本信息

  • 批准号:
    8453501
  • 负责人:
  • 金额:
    $ 19.38万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2012
  • 资助国家:
    美国
  • 起止时间:
    2012-09-26 至 2013-02-28
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Errors in the administration of medications to residents of long-term care facilities (LTCFs) threaten resident safety and add significant unnecessary costs to the healthcare system. Use of unit dose medications that require LTCF staff to manually sort and assemble specific patient medications ~4 times per day can result in error rates as high as 42%, with 7% of total errors having significant potential for harm. Just preparing medications for administration consumes an estimated 6-8 person hours/day in a typical 100 resident LTCF, or an estimated 16,000 full time equivalents in all US LTCFs, reducing staff time available for other functions. Another unnecessary cost, estimated at $5 billion in US nursing homes alone, arises from medications that are wasted due to prescription changes and patient turnover. New regulations from the Centers for Medicare and Medicaid Services, effective 1 January 2013, target reduced medication waste by requiring "short cycle" fills (d14 days) instead of the traditional 30 day "bingo cards". However, even if this has the desired result of reducing prescription drug waste, industry sources predict that use of shorter cycle bingo cards may increase LTCF staff time and possibly errors associated with manual sorting of unit dose packaging. Proposed Solution: Short-cycle custom medication packaging (CMP), containing all the "right medications needed for the right patient at the right time", has the potential to reduce risk of medication errors and LTCF staff time required for medication assembly as well as prescription drug waste. Altaic's goal is to create the Pill Stream, a novel robot for high accuracy, high throughput production of CMPs in a variety of facility-specified formats, enabling more Central-Fill (C-F) pharmacies to provide their LTCF customers with shorter turnaround times at reduced cost. Specific Aims: In this 6-month Phase I SBIR we propose to 1) to build a small scale prototype of the PillStream, and 2) evaluate its performance with respect to CMP filling accuracy, rate of production, and costs. The PillStream will incorporate proven advanced agile manufacturing technology, utilized in Artaic's successful TileJet robot developed for high speed low-cost mosaic manufacturing. Feasibility of PillStream approach will be demonstrated if the prototype can produce CMP blisters containing different mixtures of pills at a rate of at least 100 CMP blisters/min with an accuracy of at least 99.9%. Assuming Phase I success, in Phase II we will develop a commercial scale PillStream capable of handling 50% of the workload of a typical C-F pharmacy, and pilot it in two C-F pharmacies serving a total of 10,000 beds. PUBLIC HEALTH RELEVANCE: Current packaging of prescription medications provided to long-term care facilities (LTCFs) by central fill pharmacies generally utilizes unit dose packaging. This requires LTCF staff to manually assemble the medications to be taken by a given resident at each administration time (typically 7-12 medications and 4 times per day), a task that: 1) is associated with high error rates, some harmful to the recipient; 2) significantly decreases time available for other nursing functions; and 3) increases costs. The proposed PillStream robot is expected to allow central fill pharmacies to create custom multi-medication packaging (single blisters containing all medications required by a single resident at a single time during his/her day), thereby removing the error-prone manual assembly tasks from the LTCF staff, freeing time and reducing waste.
描述(由申请人提供):长期护理机构(LTCF)的居民用药错误威胁居民安全,并为医疗保健系统增加了大量不必要的成本。使用单位剂量药物需要LTCF工作人员每天手动分类和组装特定患者药物约4次,这可能导致错误率高达42%,其中7%的错误具有显著的潜在伤害。在一个典型的100名居民LTCF中,仅准备给药药物就消耗了估计6-8个工时/天,或者在所有美国LTCF中估计消耗了16,000个全职等效工时,减少了可用于其他功能的工作人员时间。另一个不必要的成本,估计仅在美国养老院就有50亿美元,来自由于处方变更和患者周转而浪费的药物。医疗保险和医疗补助服务中心的新规定于2013年1月1日生效,旨在通过要求“短周期”填充(d14天)而不是传统的30天“宾果卡”来减少药物浪费。然而,即使这具有减少处方药浪费的预期结果,行业消息来源预测,使用较短周期的宾果卡可能会增加LTCF工作人员的时间,并可能与单位剂量包装的手动分拣相关的错误。建议的解决方案:短周期定制药物包装(CMP)包含所有“在正确的时间为正确的患者提供所需的正确药物”,有可能减少用药错误的风险和LTCF工作人员组装药物所需的时间以及处方药浪费。Altaic的目标是创建Pill Stream,这是一种新颖的机器人,用于高精度,高通量生产各种设施指定格式的CMP,使更多的中央填充(C-F)药店能够以更低的成本为LTCF客户提供更短的周转时间。具体目标:在本为期6个月的第I阶段SBIR中,我们建议1)构建PillStream的小规模原型,2)评价其在CMP填充精度、生产率和成本方面的性能。PillStream将采用经过验证的先进敏捷制造技术,用于Artaic成功的TileJet机器人,用于高速低成本马赛克制造。如果原型能够以至少100个CMP泡罩/min的速率生产含有不同药丸混合物的CMP泡罩,且准确度至少为99.9%,则将证明PillStream方法的可行性。假设第一阶段取得成功,在第二阶段,我们将开发一个商业规模的PillStream,能够处理一个典型的C-F药房50%的工作量,并在两个C-F药房试点,共提供10,000张床位。 公共卫生相关性:由中心填充药房提供给长期护理机构(LTCF)的处方药的当前包装通常利用单位剂量包装。这需要LTCF工作人员在每个给药时间手动组装给定居民要服用的药物(通常7-12种药物,每天4次),这是一项任务:1)与高错误率相关,一些对接受者有害; 2)显著减少可用于其他护理功能的时间;以及3)增加成本。拟议的PillStream机器人预计将允许中心填充药房创建定制的多药物包装(单个泡罩包含单个居民在一天中的单个时间所需的所有药物),从而消除LTCF工作人员容易出错的手动组装任务,节省时间并减少浪费。

项目成果

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Edward Acworth其他文献

Edward Acworth的其他文献

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{{ truncateString('Edward Acworth', 18)}}的其他基金

PillStream: Agile High-Throughput Assembly of Custom Multi-Medication Packaging
PillStream:定制多种药物包装的敏捷高通量组装
  • 批准号:
    8649102
  • 财政年份:
    2013
  • 资助金额:
    $ 19.38万
  • 项目类别:
PillStream: Agile High-Throughput Assembly of Custom Multi-Medication Packaging
PillStream:定制多种药物包装的敏捷高通量组装
  • 批准号:
    8743825
  • 财政年份:
    2013
  • 资助金额:
    $ 19.38万
  • 项目类别:
PillStream: Agile High-Throughput Assembly of Custom Multi-Medication Packaging
PillStream:定制多种药物包装的敏捷高通量组装
  • 批准号:
    8792095
  • 财政年份:
    2013
  • 资助金额:
    $ 19.38万
  • 项目类别:

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