Training in Animal Models of Inflammation

炎症动物模型的训练

基本信息

  • 批准号:
    8311630
  • 负责人:
  • 金额:
    $ 16.61万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-09-01 至 2016-08-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Inflammation plays a central role in the development of most, if not all, human diseases. Animal models are critical in understanding the intercellular communication driving and regulating inflammation as well as the impact of acute or chronic inflammation on disease progression. Faculty in the training program have overlapping interests in studying the molecular regulation of inflammation as it pertains to the progression of autoimmune disease, allergy, immunity to infection, nutrition, carcinogenesis and mechanisms of toxicity. The combined skills and knowledge of our faculty will provide unique opportunities for students in the program to develop comprehensive state-of-the-art skills in the use of animal models to tackle complex issues in the molecular regulation of inflammation, an understanding of their relationship of these models to human disease, and the potential therapeutic applications generated by these models. The skills learned here will position students competitively for future careers in the study of inflammation and its impact on human health and disease. Currently there are only two active training grants on the Penn State University Park campus (Family Demography, and Prevention and Methodology). This training program will provide critical resources and the commitment to expand and advance pre-doctoral training in the biomedical sciences at Penn State. The program will positively impact the students in the training program by providing broad-based training in the molecular regulation of inflammation in many disease models. The program will also benefit students in the biomedical sciences across the Penn State University Park campus by enhancing the learning environment and increasing the overall visibility of biomedical research. In light of these goals, this proposal has three specific aims: Specific Aim 1. Provide outstanding students with comprehensive training in the use of animal models to study the molecular regulation of inflammation and its effect on disease progression. Specific Aim 2. Provide students with an in-depth understanding of the potential application of these animal models to human health and disease. Specific Aim 3. Increase the visibility of biomedical research at the Penn State University Park campus, and enhance the learning environment for students and faculty at Penn State.
描述(由申请人提供):炎症在大多数(如果不是全部)人类疾病的发展中起着核心作用。动物模型对于理解细胞间通讯驱动和调节炎症以及急性或慢性炎症对疾病进展的影响至关重要。培训计划的教师在研究炎症的分子调控方面有重叠的兴趣,因为它涉及自身免疫性疾病,过敏,感染免疫,营养,致癌和毒性机制的进展。我们教师的综合技能和知识将为该计划的学生提供独特的机会,以发展全面的最先进的技能,使用动物模型来解决炎症分子调控中的复杂问题,了解这些模型与人类疾病的关系,以及这些模型产生的潜在治疗应用。在这里学到的技能将使学生在炎症及其对人类健康和疾病的影响的研究中具有竞争力。目前,在宾夕法尼亚州立大学公园校区只有两个有效的培训赠款(家庭人口统计学和预防与方法学)。该培训计划将提供关键资源,并致力于扩大和推进宾夕法尼亚州立大学生物医学科学的博士前培训。该计划将通过在许多疾病模型中提供炎症分子调控的广泛培训,对培训计划中的学生产生积极影响。该计划还将通过改善学习环境和提高生物医学研究的整体知名度,使整个宾夕法尼亚州立大学公园校区的生物医学科学学生受益。根据这些目标,本提案有三个具体目标:具体目标1。为优秀学生提供使用动物模型的全面培训,以研究炎症的分子调节及其对疾病进展的影响。具体目标2。让学生深入了解这些动物模型对人类健康和疾病的潜在应用。具体目标3。提高生物医学研究在宾夕法尼亚州立大学公园校区的知名度,并改善学生和教师在宾夕法尼亚州立大学的学习环境。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Pamela A Giblin其他文献

Pamela A Giblin的其他文献

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{{ truncateString('Pamela A Giblin', 18)}}的其他基金

Role of Gab1 and Gab2 in Stress Erythropoiesis
Gab1 和 Gab2 在应激性红细胞生成中的作用
  • 批准号:
    8439536
  • 财政年份:
    2012
  • 资助金额:
    $ 16.61万
  • 项目类别:
Training in Animal Models of Inflammation
炎症动物模型的训练
  • 批准号:
    8668883
  • 财政年份:
    2011
  • 资助金额:
    $ 16.61万
  • 项目类别:
Training in Animal Models of Inflammation
炎症动物模型的训练
  • 批准号:
    8151727
  • 财政年份:
    2011
  • 资助金额:
    $ 16.61万
  • 项目类别:
Training in Animal Models of Inflammation
炎症动物模型的训练
  • 批准号:
    8890077
  • 财政年份:
    2011
  • 资助金额:
    $ 16.61万
  • 项目类别:
Training in Animal Models of Inflammation
炎症动物模型的训练
  • 批准号:
    8502606
  • 财政年份:
    2011
  • 资助金额:
    $ 16.61万
  • 项目类别:
Role of the STK Receptor in Erythropoiesis
STK 受体在红细胞生成中的作用
  • 批准号:
    7819133
  • 财政年份:
    2009
  • 资助金额:
    $ 16.61万
  • 项目类别:
Alcorn State University: Penn State University Bridges to the Doctorate Program
奥尔康州立大学:宾夕法尼亚州立大学通往博士学位课程的桥梁
  • 批准号:
    8137905
  • 财政年份:
    2006
  • 资助金额:
    $ 16.61万
  • 项目类别:
Alcorn State University: Penn State University Bridges to the Doctorate Program
奥尔康州立大学:宾夕法尼亚州立大学通往博士学位课程的桥梁
  • 批准号:
    8324545
  • 财政年份:
    2006
  • 资助金额:
    $ 16.61万
  • 项目类别:
Alcorn State University: Penn State University Bridges to the Doctorate Program
奥尔康州立大学:宾夕法尼亚州立大学通往博士学位课程的桥梁
  • 批准号:
    7936470
  • 财政年份:
    2006
  • 资助金额:
    $ 16.61万
  • 项目类别:
Alcorn State University: Penn State University Bridges to the Doctorate Program
奥尔康州立大学:宾夕法尼亚州立大学通往博士学位课程的桥梁
  • 批准号:
    8543743
  • 财政年份:
    2006
  • 资助金额:
    $ 16.61万
  • 项目类别:

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Inclusive Excellence Training Program in the Systems Biology of Cardiovascular Inflammation
心血管炎症系统生物学包容性卓越培训计划
  • 批准号:
    10555753
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  • 批准号:
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脓毒症片上骨骼肌微组织模型中抗阻训练与炎症之间的竞争
  • 批准号:
    10091023
  • 财政年份:
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Competition between Resistance Training and Inflammation in an On-Chip Skeletal Muscle Microtissue Model of Sepsis
脓毒症片上骨骼肌微组织模型中抗阻训练与炎症之间的竞争
  • 批准号:
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感染和炎症作为衰老驱动因素 (IIDA) 博士前培训计划
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感染和炎症作为衰老驱动因素 (IIDA) 博士前培训计划
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12 周高强度阻力有氧循环运动训练对老年 HIV 感染退伍军人表观遗传衰老和炎症的影响
  • 批准号:
    10382206
  • 财政年份:
    2019
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    $ 16.61万
  • 项目类别:
Effects of 12-weeks of High-intensity Resistance Aerobic Circuit Exercise Training on Epigenetic Aging and Inflammation in Older HIV-infected Veterans
12 周高强度阻力有氧循环运动训练对老年 HIV 感染退伍军人表观遗传衰老和炎症的影响
  • 批准号:
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