DEVELOPMENT FUNDS

发展基金

• 批准号: 8378379
• 负责人: KRISTIINA VUORI
• 金额: $ 55.74万
• 依托单位: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-21 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8378379
• 关键词: Applications Grants; Area; Award; Biology; Cancer Center; Cancer Center Support Grant; Chemicals; Collaborations; Commit; Development; Direct Costs; Evaluation; Faculty; Funding; Future; Grant; Institutes; Investments; Laboratory Research; Mission; Pilot Projects; Price; Process; Publications; Rana; Recruitment Activity; Research; Research Personnel; Research Support; Resource Sharing; Resources; Scientist; Source; Wages; Wolves; anticancer research; cost; experience; functional genomics; member

CCSG developmental funds during this past project period have enabled new junior faculty to successfully establish their research laboratories at the Institute. These funds have also helped relocate several established investigators to the Institute. The 11 faculty who received developmental funds from the CCSG grant during this past project period include Drs. Oldham, Z. Huang, Price, Ronai, Courtneidge, Riedl, Wolf, Cang, Petroski, Cosford, and Lee. A total of $2.1 MM of direct CCSG support was provided to these recruits over the last five years. The remainder of the recruitment commitment for these investigators is covered by the Institute. In addition, the Institute fully supported the recruitment of the following 10 Cancer Center members: Drs. Bodmer, Chanda, Hansen, Komatsu, Levine, Puri, Rana, Rickert, Terskikh, and Xu. Altogether, over $,17MM in total costs (direct funds and corresponding overhead) of institutional funds have been expended or committed in future years towards these 21 new Cancer Center members. The new Center members have been awarded total direct grant funds of over $27MM during this period, demonstrating a remarkable return on investment for our Developmental Funds. CCSG developmental funds were also used for pilot project grants, promoting collaborations and developing projects that enabled new research directions of strategic importance to the Center, and the accumulation of sufficient preliminary results to support new grant initiatives and publications. Pilot project funds were provided to Drs. Terskikh, Marassi, Ronai, Feng, Oshima, Cang, Reed, Jiang, Yamamoto, Hansen, Wolf, Osterman, Smith, Stallcup, Pasquale, Ranscht, and Millan. Also, several 'mini-projects' were funded, allowing the award recipients to take advantage of our cutting-edge Shared Resources, again enabling new research directions, and submission of grant applications and publications. Lastly, CCSG funds were used to support the establishment of a new Shared Resource, Functional Genomics. This Shared Resource is now fully operational, and widely used by Cancer Center members. During the next project period, we expect to add 10-12 new investigators to the Cancer Center. We request support for two new Cancer Center faculty per year at $175,000 each ($350,000 total per year) for salary support, support for postdoctoral associates, and supplies. This is less than 20% of the expected total cost; the remainder of the recruitment commitment will be provided from institutional sources. Support is also requested for 2-3 pilot projects annually at $50,000-$75,000 each ($150,000 total per year) for collaborative pilot grants and for pilot grants under the Chemical Biology Initiative. Total Developmental Funds requested: $500,000.

在过去的项目期间，CCSG发展基金使新的初级教师成功地 在研究所建立自己的研究实验室。这些资金还帮助重新安置了几个 研究所的调查员。从CCSG获得发展资金的11名教师 在过去的项目期间获得资助的包括奥尔德姆博士，Z。黄，普莱斯，罗奈，考特尼奇，里德尔，沃尔夫， 康，佩特斯基，科斯福德，还有李.向这些新聘人员提供了总额为210万美元的CCSG直接支助 在过去的五年里。这些调查员的征聘承诺的其余部分由 研究所。此外，研究所全力支持以下10个癌症中心的招聘工作 成员：Bodmer、Chanda、汉森、小松、Levine、Puri、Rana、里克特、Terskikh和Xu博士。 机构资金的总成本（直接资金和相应的管理费用）总计超过1700万美元， 在未来的几年里，我们将为这21名新的癌症中心成员提供或承诺。新中心 在此期间，成员已获得超过2700万美元的直接赠款， 为我们的发展基金带来了可观的投资回报。 CCSG发展基金还用于试点项目赠款，促进合作和发展 项目，使新的研究方向的战略重要性，以中心，和积累 有足够的初步结果来支持新的赠款倡议和出版物。试点项目资金 提供给Terskikh、Marassi、Ronai、Feng、Oshima、Cang、Reed、Jiang、Yamamoto、汉森、Wolf博士， 奥斯特曼，史密斯，斯塔卡普，帕斯夸尔，兰斯特和米兰。此外，还资助了几个"小型项目"， 获奖者利用我们的尖端共享资源，再次使新的研究 指导，并提交赠款申请和出版物。最后，CCSG资金用于支持 建立新的共享资源，功能基因组学。此共享资源现已完全 操作，并被癌症中心成员广泛使用。 在下一个项目期间，我们预计将增加10 - 12名新的研究人员到癌症中心。我们要求 支持两个新的癌症中心教师每年175,000美元（每年350,000美元）的工资 支持，支持博士后助理，和用品。这不到预期总费用的20%; 其余的招聘承诺将由机构提供。支持也是 要求每年开展2 - 3个试点项目，每个项目50 000 - 75 000美元（每年共计150 000美元）， 试点赠款和化学生物学倡议下的试点赠款。申请的发展资金总额： 五十万