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中文摘要
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描述(由申请人提供):住院吸烟者发生与持续吸烟相关并发症的风险较高。尽管全国都在关注住院患者的戒烟问题,但农村医院一直无法实施有效戒烟计划的完整组成部分。在这一具有竞争力的更新中,我们经验丰富的多学科团队将建立在我们在农村社区戒烟研究的坚实基础上。Kan Quit针对准备戒烟的所有阶段的吸烟者,表明疾病管理,其中免费药物治疗与药物治疗管理相结合,可以使78%的吸烟者获得有效治疗。不幸的是,戒烟的免费药物治疗并不普遍。国家戒烟计划的供应有限,提供的选择有限;虽然药物治疗的处方覆盖率越来越高,但未得到充分利用,特别是在住院吸烟的高危人群中。基于慢性病护理模式,我们修订的疾病管理计划旨在提供咨询和疾病管理,同时增加药物治疗的利用率并加强医疗保健提供者的支持。与Kan Quit相比,我们修订后的疾病管理计划将利用社区现有的药物治疗资源。我们的具体目标是:1)评估集中疾病管理(CDM)在住院的农村吸烟者中戒烟的有效性; 2)测试CDM对药物治疗利用的影响,并与卫生保健提供者进行讨论; 3)阐明这些因素的利用如何介导CDM对戒烟的影响; 4)检查CDM戒烟的边际成本效益。本研究将在堪萨斯的30家农村危重病医院进行。主要结局是经唾液可替宁证实的7天时点戒烟率。住院的农村吸烟者将被随机分配到CDM或单独咨询(C)组(每组303例)。所有受试者将在第3、7、21和90天接受住院电话咨询和电话随访。6个月后,将再次努力重新吸引持续或复吸的吸烟者。对于CDM参与者,我们的烟草治疗专家还将在住院期间和出院后提供基于电话的疾病管理,包括与其保险计划一致的药物治疗的补充支持,以及与其医疗保健提供者建立有效讨论的指导。烟草治疗专家还将向医疗保健提供者传真治疗建议,处方请求和咨询建议。拟议的研究将提高我们对戒烟疾病管理的理解,如果成功,有可能立即在农村关键医院实施。公共卫生相关性:许多住院吸烟者没有得到有效的戒烟治疗。在对Kan Quit的随访中,我们将了解住院吸烟者的疾病管理是否可以增加有效药物治疗的使用,改善与医疗保健提供者的沟通,并提高戒烟率。
英文摘要
DESCRIPTION (provided by applicant): Hospitalized smokers are at high risk for complications related to continued tobacco use. Although national attention has been directed at smoking cessation for hospitalized patients, rural hospitals have been unable to implement the complete components of effective smoking cessation programs. In this competitive renewal to Kan Quit, our experienced, multidisciplinary team will build upon our strong foundation of research on smoking cessation in rural communities. Kan Quit, directed at smokers in all stages of readiness to quit, demonstrated that disease management, in which free pharmacotherapy was combined with pharmacotherapy management, could engage 78% of smokers in effective treatment. Unfortunately, free pharmacotherapy for smoking cessation is not universally available. State smoking cessation programs have limited supplies and offer limited choices; although prescription coverage for pharmacotherapy is increasingly available, it is underutilized, particularly among the high-risk population of hospitalized smokers. Grounded in the Chronic Care Model, our revised disease management program is designed to provide counseling and disease management while increasing utilization of pharmacotherapy and enhancing support from healthcare providers. In contrast to Kan Quit, our revised disease management program will take advantage of resources for pharmacotherapy already available in the community. Our specific objectives are to 1) evaluate the effectiveness of Centralized Disease Management (CDM) for smoking cessation among hospitalized rural smokers; 2) test the impact of CDM on utilization of pharmacotherapy and discussions with health care providers; 3) clarify how utilization of these elements may mediate the effect of CDM on smoking cessation; and 4) examine the marginal cost effectiveness of CDM for smoking cessation. This study will be conducted in 30 rural critical access hospitals in Kansas. The primary outcome is 7-day point prevalence abstinence confirmed by salivary cotinine. Hospitalized rural smokers will be randomized to either CDM or counseling (C) alone (303 in each arm). All participants will receive in-hospital telephone counseling with telephone follow-up at days 3, 7, 21, and 90. A second effort will be made to re-engage persistent or relapsed smokers 6 months later. For CDM participants, our Tobacco Treatment Specialist will also provide telephone-based disease management during the hospitalization and after discharge, including supplemental support for pharmacotherapy that is consistent with their insurance plan and guidance on establishing effective discussions with their health care provider. The Tobacco Treatment Specialist will also fax treatment recommendations, prescription requests, and counseling suggestions to the healthcare provider. The proposed research will enhance our understanding of disease management for smoking cessation and, if successful, has the potential for immediate implementation in rural critical access hospitals. PUBLIC HEALTH RELEVANCE: Many hospitalized smokers do not receive effective smoking cessation treatment. In this follow-up to Kan Quit we will see if disease management for hospitalized smokers can increase use of effective pharmaco- therapy, improve communication with health care providers, and increase rates of smoking cessation.
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Implementation Science and Equity: Pragmatic Implementation Science Methods (PrISM) Core
Frontiers: University of Kansas Clinical and Translational Science Institute
Frontiers: University of Kansas Clinical and Translational Science Institute
Institutional Career Development Core
国内基金
海外基金
多模态超声VisTran-Attention网络评估早期子宫颈癌保留生育功能手术可行性
  • 批准号:
    --
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    30万元
  • 批准年份:
    2022
  • 负责人:
    郑巧
  • 依托单位:
Ultrasomics-Attention孪生网络早期精准评估肝内胆管癌免疫治疗的研究
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    52万元
  • 批准年份:
    2022
  • 负责人:
    陈立达
  • 依托单位: