Barbershop-Based HIV/STD Risk Reduction for African American Young Men

基于理发店的非洲裔美国年轻男性艾滋病毒/性病风险降低

• 批准号: 8323750
• 负责人: LORETTA Sweet JEMMOTT
• 金额: $ 6.93万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8323750
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Affect; African American; Age-Years; Attitude; Behavior; Behavior Control; Behavior Therapy; Behavioral; Belief; Characteristics; Code; Coitus; Communities; Computer Assisted; DNA amplification; Data; Education; Enrollment; Focus Groups; Frequencies; Gender; HIV; Heterosexuals; Hour; Human immunodeficiency virus test; Incidence; Intervention; Intervention Studies; Interview; Knowledge; Link; Mediating; Mediation; Mediator of activation protein; Multiple Partners; Outcome; Outcome Measure; Participant; Patient Self-Report; Philadelphia; Planning Theory; Population; Population Intervention; Population Research; Population Study; Preventive Intervention; Public Health; Randomized; Randomized Controlled Trials; Request for Applications; Research; Research Design; Risk; Risk Reduction; Self Efficacy; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Solid; Specimen; Surveys; Testing; United States; Urine; Vagina; Woman; Youth; base; behavior change; condoms; consistent condom use; design; disorder risk; efficacy testing; follow-up; group intervention; high risk; intervention effect; male; men; post intervention; primary outcome; public health relevance; response; secondary outcome; sex; sex risk; social cognitive theory; theories; therapy development; transmission process; violence prevention; young man

DESCRIPTION (provided by applicant): This application is submitted in response to Request for Applications RFA-HD-08-013, "Gender, Youth and HIV Risk (R01)." The broad, long-term objective of the proposed research is to develop and test the efficacy of a theory-based, culturally and contextually competent, and gender-specific behavioral intervention to reduce the risk of sexually transmitted diseases (STDs), including HIV, among African American young men 18 to 24 years of age. The Specific Aims are focused on testing the intervention's effects on sexual behavior and STD incidence and testing the mediation of effects of the intervention. African American young men have some of the highest rates of STDs among men in the United States. Efforts to reduce their risk of STD have been hampered by the lack of sexual risk-reduction interventions with solid evidence of efficacy and the inability to identify how to reach this population. We propose to test an intervention for this population in barbershops, which may be an excellent setting in which to engage African American young men in risk-reduction education. The design of the study is a cluster randomized controlled trial. We will stratify on key characteristics, barbershops in zip codes of Philadelphia, PA with the highest rates of AIDS and match them in pairs. We will randomly select 24 matched-pairs and within each pair, randomly assign the barbershops to one of two brief structurally similar small-group interventions led by a male barber facilitator: a 3-hour HIV/STD Risk-Reduction Intervention or a 3-hour violence prevention intervention that will serve as the control. We will enroll in the trial 24 men from each barbershop, for a total of 1,152 participants. Social cognitive theory, the theory of reasoned action/planned behavior, and the applicant's preliminary studies with the population will guide the development of the intervention. The primary outcomes are self-reported condom use, multiple sexual partners, unprotected sexual intercourse, and sexual intercourse assessed at baseline and 6- and 12-month follow-up via audio computer-assisted self-interviewing (ACASI). Secondary outcomes include STDs based on DNA amplification tests on urine specimens and theoretically relevant variables hypothesized to mediate intervention effects, including intentions, beliefs, and self-efficacy. The proposed research has great public health significance: about one-half the cases of HIV/AIDS worldwide are linked to sexual relations between men and women, but few randomized controlled trials have tested HIV/STD risk-reduction interventions specific to young men who have sex with women. This research will test the efficacy of such an intervention in one of the highest risk populations in the United States. PUBLIC HEALTH RELEVANCE: This research has great public health relevance. Although about one-half the HIV/AIDS cases worldwide are tied to sexual relations between men and women, few sexual risk-reduction intervention studies have targeted men and fewer still have targeted men 18 to 24 years of age. Moreover, the population this research targets, African American young men, has some of the highest rates of HIV and STDs in the US.

描述(由申请人提供)：本申请是应申请RFA-HD-08-013“性别、青年和艾滋病毒风险(R01)”的请求而提交的。这项拟议研究的广泛、长期目标是开发和测试一种基于理论、在文化和背景下有能力的、针对性别的行为干预的有效性，以降低18至24岁的非裔美国青年男子感染包括艾滋病毒在内的性传播疾病(STDS)的风险。具体目的是检验干预对性行为和性病发病率的影响，并检验干预效果的中介作用。在美国男性中，非裔美国年轻人的性病发病率最高。由于缺乏有确凿证据证明有效的降低风险的性干预措施，以及无法确定如何接触到这一人群，降低他们患性病风险的努力受到了阻碍。我们建议在理发店测试针对这一人群的干预措施，这可能是让非裔美国年轻人参与降低风险教育的一个很好的环境。研究设计为整群随机对照试验。我们将根据关键特征进行分层，将爱滋病发病率最高的宾夕法尼亚州费城邮政编码的理发店进行配对。我们将随机选择24对配对，在每对配对中，随机将理发店分配到由男性理发师领导的两个结构相似的简短小组干预中的一个：作为对照的3小时艾滋病毒/性传播疾病风险降低干预或3小时暴力预防干预。我们将从每家理发店招募24名男性参加试验，总共有1152名参与者。社会认知理论、合理行动/计划行为理论以及申请者对人群的初步研究将指导干预的发展。主要结果是自我报告的避孕套使用，多个性伴侣，无保护的性交，以及在基线和通过音频计算机辅助自我访谈(ACASI)评估的6个月和12个月的随访性交。次要结果包括基于尿样DNA扩增测试的性传播疾病，以及理论上假设的调节干预效果的相关变量，包括意图、信念和自我效能。这项拟议的研究具有重大的公共卫生意义：全球约有一半的艾滋病毒/艾滋病病例与男性和女性之间的性关系有关，但很少有随机对照试验测试针对与女性发生性行为的年轻男性的艾滋病毒/性传播疾病风险降低干预措施。这项研究将在美国风险最高的人群之一测试这种干预的效果。 公共卫生相关性：这项研究具有很大的公共卫生相关性。尽管全球约有一半的艾滋病毒/艾滋病病例与男性和女性之间的性关系有关，但针对男性的降低性风险干预研究很少，针对18至24岁的男性的更少。此外，这项研究的目标人群是非裔美国青年男性，他们的艾滋病毒和性传播疾病的发病率在美国是最高的。