Barbershop-Based HIV/STD Risk Reduction for African American Young Men

基于理发店的非洲裔美国年轻男性艾滋病毒/性病风险降低

• 批准号: 8617852
• 负责人: LORETTA Sweet JEMMOTT
• 金额: $ 82.25万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2015-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8617852
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Affect; African American; Age-Years; Attitude; Behavior; Behavior Control; Behavior Therapy; Behavioral; Belief; Characteristics; Code; Coitus; Communities; Computer Assisted; DNA amplification; Data; Education; Enrollment; Focus Groups; Frequencies; Gender; HIV; HIV risk; Heterosexuals; Hour; Human immunodeficiency virus test; Incidence; Intervention; Intervention Studies; Interview; Knowledge; Link; Mediating; Mediation; Mediator of activation protein; Multiple Partners; Outcome; Outcome Measure; Participant; Patient Self-Report; Philadelphia; Planning Theory; Population; Population Intervention; Population Research; Population Study; Preventive Intervention; Public Health; Randomized; Randomized Controlled Trials; Request for Applications; Research; Research Design; Risk; Risk Reduction; Self Efficacy; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Solid; Specimen; Surveys; Testing; United States; Urine; Vagina; Woman; Youth; base; behavior change; condoms; consistent condom use; design; disorder risk; efficacy testing; follow-up; group intervention; high risk; intervention effect; male; men; post intervention; primary outcome; public health relevance; response; secondary outcome; sex; sex risk; social cognitive theory; theories; therapy development; transmission process; violence prevention; young man

DESCRIPTION (provided by applicant): This application is submitted in response to Request for Applications RFA-HD-08-013, "Gender, Youth and HIV Risk (R01)." The broad, long-term objective of the proposed research is to develop and test the efficacy of a theory-based, culturally and contextually competent, and gender-specific behavioral intervention to reduce the risk of sexually transmitted diseases (STDs), including HIV, among African American young men 18 to 24 years of age. The Specific Aims are focused on testing the intervention's effects on sexual behavior and STD incidence and testing the mediation of effects of the intervention. African American young men have some of the highest rates of STDs among men in the United States. Efforts to reduce their risk of STD have been hampered by the lack of sexual risk-reduction interventions with solid evidence of efficacy and the inability to identify how to reach this population. We propose to test an intervention for this population in barbershops, which may be an excellent setting in which to engage African American young men in risk-reduction education. The design of the study is a cluster randomized controlled trial. We will stratify on key characteristics, barbershops in zip codes of Philadelphia, PA with the highest rates of AIDS and match them in pairs. We will randomly select 24 matched-pairs and within each pair, randomly assign the barbershops to one of two brief structurally similar small-group interventions led by a male barber facilitator: a 3-hour HIV/STD Risk-Reduction Intervention or a 3-hour violence prevention intervention that will serve as the control. We will enroll in the trial 24 men from each barbershop, for a total of 1,152 participants. Social cognitive theory, the theory of reasoned action/planned behavior, and the applicant's preliminary studies with the population will guide the development of the intervention. The primary outcomes are self-reported condom use, multiple sexual partners, unprotected sexual intercourse, and sexual intercourse assessed at baseline and 6- and 12-month follow-up via audio computer-assisted self-interviewing (ACASI). Secondary outcomes include STDs based on DNA amplification tests on urine specimens and theoretically relevant variables hypothesized to mediate intervention effects, including intentions, beliefs, and self-efficacy. The proposed research has great public health significance: about one-half the cases of HIV/AIDS worldwide are linked to sexual relations between men and women, but few randomized controlled trials have tested HIV/STD risk-reduction interventions specific to young men who have sex with women. This research will test the efficacy of such an intervention in one of the highest risk populations in the United States. PUBLIC HEALTH RELEVANCE: This research has great public health relevance. Although about one-half the HIV/AIDS cases worldwide are tied to sexual relations between men and women, few sexual risk-reduction intervention studies have targeted men and fewer still have targeted men 18 to 24 years of age. Moreover, the population this research targets, African American young men, has some of the highest rates of HIV and STDs in the US.

描述（由申请人提供）：本申请是根据申请请求RFA-HD-08-013，“性别，青年和艾滋病毒风险（R01）”提交的。拟议研究的广泛和长期目标是开发和测试一种基于理论的、具有文化和背景能力的、针对性别的行为干预措施的效果，以降低18至24岁的非裔美国青年男子感染包括艾滋病毒在内的性传播疾病的风险。具体目的是测试干预对性行为和性病发病率的影响，以及测试干预效果的中介作用。在美国男性中，非裔美国年轻男性的性传播疾病发病率最高。由于缺乏具有有效证据的降低性风险干预措施，以及无法确定如何向这一人群提供干预措施，降低他们患性病风险的努力受到了阻碍。我们建议在理发店对这一人群进行干预测试，理发店可能是一个很好的环境，可以让非洲裔美国年轻人参与减少风险的教育。本研究设计为整群随机对照试验。我们将对关键特征进行分层，费城邮政编码的理发店，PA艾滋病发病率最高，并将它们配对。我们将随机选择24对配对的理发店，在每对配对中，将理发店随机分配到由男性理发师主持的两种结构相似的简短小组干预中的一种：3小时的艾滋病毒/性病风险降低干预或3小时的暴力预防干预，作为对照。我们将从每家理发店招募24名男性参加试验，总共有1152名参与者。社会认知理论、理性行动/计划行为理论以及申请人对人群的初步研究将指导干预的发展。主要结果是自我报告的安全套使用情况、多个性伴侣、无保护的性交情况，以及通过音频计算机辅助自我访谈（ACASI）在基线和6个月和12个月随访时评估的性交情况。次要结果包括基于尿液样本DNA扩增测试的性传播疾病，以及假设介导干预效果的理论相关变量，包括意图、信念和自我效能感。拟议的研究具有重大的公共卫生意义：全世界大约一半的艾滋病毒/艾滋病病例与男女之间的性关系有关，但是很少有随机对照试验测试了专门针对与女性发生性关系的年轻男性的降低艾滋病毒/性病风险的干预措施。这项研究将测试这种干预在美国最高风险人群之一的有效性。