Barbershop-Based HIV/STD Risk Reduction for African American Young Men

基于理发店的非洲裔美国年轻男性艾滋病毒/性病风险降低

• 批准号: 7905784
• 负责人: LORETTA Sweet JEMMOTT
• 金额: $ 70.63万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7905784
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Affect; African American; Age-Years; Attitude; Behavior; Behavior Control; Behavior Therapy; Behavioral; Belief; Characteristics; Code; Coitus; Communities; Computer Assisted; DNA amplification; Data; Education; Enrollment; Focus Groups; Frequencies; Gender; HIV; Heterosexuals; Hour; Human immunodeficiency virus test; Incidence; Intervention; Intervention Studies; Interview; Link; Mediating; Mediation; Mediator of activation protein; Multiple Partners; Outcome; Outcome Measure; Participant; Patient Self-Report; Philadelphia; Planning Theory; Population; Population Intervention; Population Research; Population Study; Preventive Intervention; Public Health; Randomized; Randomized Controlled Trials; Request for Applications; Research; Research Design; Risk; Risk Reduction; Self Efficacy; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Solid; Specimen; Surveys; Testing; United States; Urine; Vagina; Woman; Youth; base; behavior change; condoms; consistent condom use; design; disorder risk; efficacy testing; follow-up; group intervention; high risk; intervention effect; male; men; post intervention; primary outcome; public health relevance; response; secondary outcome; sex; sex risk; social cognitive theory; theories; therapy development; transmission process; violence prevention

DESCRIPTION (provided by applicant): This application is submitted in response to Request for Applications RFA-HD-08-013, "Gender, Youth and HIV Risk (R01)." The broad, long-term objective of the proposed research is to develop and test the efficacy of a theory-based, culturally and contextually competent, and gender-specific behavioral intervention to reduce the risk of sexually transmitted diseases (STDs), including HIV, among African American young men 18 to 24 years of age. The Specific Aims are focused on testing the intervention's effects on sexual behavior and STD incidence and testing the mediation of effects of the intervention. African American young men have some of the highest rates of STDs among men in the United States. Efforts to reduce their risk of STD have been hampered by the lack of sexual risk-reduction interventions with solid evidence of efficacy and the inability to identify how to reach this population. We propose to test an intervention for this population in barbershops, which may be an excellent setting in which to engage African American young men in risk-reduction education. The design of the study is a cluster randomized controlled trial. We will stratify on key characteristics, barbershops in zip codes of Philadelphia, PA with the highest rates of AIDS and match them in pairs. We will randomly select 24 matched-pairs and within each pair, randomly assign the barbershops to one of two brief structurally similar small-group interventions led by a male barber facilitator: a 3-hour HIV/STD Risk-Reduction Intervention or a 3-hour violence prevention intervention that will serve as the control. We will enroll in the trial 24 men from each barbershop, for a total of 1,152 participants. Social cognitive theory, the theory of reasoned action/planned behavior, and the applicant's preliminary studies with the population will guide the development of the intervention. The primary outcomes are self-reported condom use, multiple sexual partners, unprotected sexual intercourse, and sexual intercourse assessed at baseline and 6- and 12-month follow-up via audio computer-assisted self-interviewing (ACASI). Secondary outcomes include STDs based on DNA amplification tests on urine specimens and theoretically relevant variables hypothesized to mediate intervention effects, including intentions, beliefs, and self-efficacy. The proposed research has great public health significance: about one-half the cases of HIV/AIDS worldwide are linked to sexual relations between men and women, but few randomized controlled trials have tested HIV/STD risk-reduction interventions specific to young men who have sex with women. This research will test the efficacy of such an intervention in one of the highest risk populations in the United States. PUBLIC HEALTH RELEVANCE: This research has great public health relevance. Although about one-half the HIV/AIDS cases worldwide are tied to sexual relations between men and women, few sexual risk-reduction intervention studies have targeted men and fewer still have targeted men 18 to 24 years of age. Moreover, the population this research targets, African American young men, has some of the highest rates of HIV and STDs in the US.

描述（由申请人提供）：本申请是为了回应申请请求RFA-HD-08-013，“性别，青年和艾滋病毒风险（R 01）。“拟议研究的广泛，长期目标是开发和测试基于理论，文化和背景能力，以及性别特异性行为干预的有效性，以降低性传播疾病（STD）的风险，包括艾滋病毒，在18至24岁的非洲裔美国年轻男性中。具体目标是检验干预措施对性行为和性病发病率的影响，检验干预措施对性行为和性病发病率的中介作用。在美国，非洲裔美国年轻男性的性病发病率最高。由于缺乏有效证据确凿的减少性风险干预措施，以及无法确定如何接触到这一人群，降低其性病风险的努力受到阻碍。我们建议在理发店测试这一人群的干预措施，这可能是一个很好的环境，让非洲裔美国年轻人参与减少风险的教育。研究设计为整群随机对照试验。我们将对关键特征进行分层，宾夕法尼亚州费城邮政编码中艾滋病发病率最高的理发店，并将它们配对。我们将随机选择24对配对，并在每对中，随机分配理发店两个简短的结构相似的小团体干预之一，由男性理发师主持人领导：一个3小时的艾滋病毒/性病风险降低干预或3小时的暴力预防干预，将作为控制。我们将从每家理发店招募24名男性参加试验，总共有1,152名参与者。社会认知理论、理性行动/计划行为理论以及申请人对人群的初步研究将指导干预措施的制定。主要结果是自我报告的安全套使用，多个性伴侣，无保护性交，并在基线和6个月和12个月的随访通过音频计算机辅助自我访谈（ACASI）评估性交。次要结果包括基于尿液样本DNA扩增测试的性病和理论上相关的变量，假设调解干预效果，包括意图，信念和自我效能。这项拟议中的研究具有重大的公共卫生意义：全世界约有一半的艾滋病毒/艾滋病病例与男女之间的性关系有关，但很少有随机对照试验测试专门针对与女性发生性关系的年轻男性的艾滋病毒/性病风险降低干预措施。这项研究将测试这种干预措施在美国最高风险人群中的有效性。 公共卫生相关性：这项研究具有很大的公共卫生相关性。虽然全世界约有一半的艾滋病毒/艾滋病病例与男女之间的性关系有关，但很少有针对男子的减少性风险干预研究，针对18至24岁男子的研究更少。此外，这项研究的目标人群，非洲裔美国年轻男子，在美国艾滋病毒和性病的发病率最高。