A new hemagglutination method for blood grouping

描述（由申请人提供）：拟议研究的长期目标是开发一种新型定量颗粒凝集技术，以提高血型分析的性能。传统的血凝血型检测方法存在灵敏度低、孵育时间长、主观性强、试剂用量大等缺点。正是在这种情况下，我们提出开发一种新的技术，它是从传统的血凝试验的上述限制自由。提出的免疫测定是一种灵敏和快速的方法，利用廉价的仪器。值得注意的是，该方法提供了一种用于增强和检测不同来源的颗粒（包括乳胶、二氧化硅微粒和生物细胞）凝集的通用方法。

DESCRIPTION (provided by applicant): The long-term goal of the proposed research is to develop a novel quantitative particle agglutination technology for improving the performance of blood typing assays. The conventional hemagglutination blood typing assays have serious drawbacks such as limited sensitivity, long time of incubation, subjectivity and large amount of reagents. It is in this context that we propose to develop a new technology, which is free from the aforementioned limitations of the conventional hemagglutination assays. The proposed immunoassay is a sensitive and rapid method that utilizes inexpensive instrumentation. Significantly, the method presents a general approach for enhancement and detection of agglutination of particles of different origin, including latex, silica microparticles, and biologial cells.