Study of Health Outcomes in Children with Autism and Their Families

自闭症儿童及其家人的健康结果研究

• 批准号: 8738804
• 负责人: TAYLOR DENNEN
• 金额: $ 49.64万
• 依托单位: LEWIN GROUP, INC.
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2014-02-27
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8738804
• 关键词: Anecdotes; Autistic Disorder; Child; Contractor; Contracts; Data; Data Set; Databases; Diagnosis; Epidemiologic Studies; Family; Family member; General Population; Health; Health Planning; Link; Modification; Outcome; Parents; Population; Prevalence; Public Health; Recording of previous events; Reporting; Research; Siblings; Surveys; United States; Vaccination; Vaccines; Work; autism spectrum disorder; cohort; health care service utilization; social communication

This contract modification is to extend and supplement Contract HHSN271201000033C, consistent with the scope of work of "Study of Health Outcomes in Children with Autism and Their Families¿ in order to access the currently validated database developed under the contract to provide for further analysis . Autism Spectrum Disorder (ASD) is a significant public health concern, with an estimated prevalence of 1 in 88 children in the United States. Much of the research to date has focused on the core social and communication deficits of ASD, but there are anecdotes and some survey data suggesting that the rate of comorbid health conditions may also be elevated in this population. Furthermore, despite several large-scale epidemiological studies that have assessed but not found any potential association between ASD and vaccinations, public concerns persist about such a causal link. At least partly as a consequence, health officials in the United States have reported an increased rate of vaccine refusal in the general population. The Study of Health Outcomes in Children with Autism and their Families was begun two years ago. Under this contract, the Contractor analyzed a large dataset of retrospective commercial health plan claims of 46,236 children with ASD, their parents and siblings, and a comparison cohort of children and family members. They successfully completed the analyses requested in the original statement of work, which included a study of the validity of ASD diagnoses in the claims data, and descriptions of health outcomes and health care utilization of the ASD cohort, their family members, and the comparison cohorts.

本合同修改是为了扩展和补充合同HHSN271201000033C，与“自闭症儿童及其家庭健康结果研究”的工作范围一致，以便访问根据合同开发的当前有效的数据库，以提供进一步的分析。