Stanford University Cancer Center

描述（由申请人提供）：斯坦福癌症中心正在向美国国家癌症研究所 (NCI) 申请五年的癌症中心支持补助金 (CCSG) 资金并指定为综合癌症中心。在过去的三年里，癌症中心的成员已从 260 名增加到 311 名，他们代表斯坦福大学的四个学院（医学、工程、人文科学和法律）以及北加州癌症中心，斯坦福大学根据正式的附属协议与北加州癌症中心建立了长期、富有成效的科学合作关系。 CCSG 提案建立在技术开发方面的机构优势之上，特别是在成像、生物技术、信息学和化学工程领域。将这些研究领域与癌症生物学、免疫学、遗传学和干细胞生物学领域相结合，开发癌症预防、诊断和治疗的新方法是该癌症中心的显着特点。十个项目涵盖癌症基础、转化/临床和群体科学研究领域（癌症生物学、放射生物学、癌症干细胞、癌症成像和早期检测、分子治疗、淋巴瘤和霍奇金病、癌症免疫学和免疫治疗、造血细胞移植和免疫重建、癌症流行病学和癌症预防和控制）。十一个共享资源支持中心进行的基础和转化/临床研究。基于目前 NCI 的基础资金 3600 万美元、5800 万美元的其他 NIH 支持以及 1600 万美元的其他同行评审的癌症相关资金，该中心请求 530 万美元的直接费用来支持其活动。随着两座用于基础和转化研究的新大楼的建成、新的招募和合作互动的增加，该中心准备在新的资助期内为癌症研究做出重大贡献。

DESCRIPTION (provided by applicant): The Stanford Cancer Center is applying to the National Cancer Institute (NCI) for five years of funding of a Cancer Center Support Grant (CCSG) and for designation as a Comprehensive Cancer Center. Over the past three years, the Cancer Center has grown from 260 to 311 members representing four Schools within Stanford University (Medicine, Engineering, Humanities and Sciences and Law) and the Northern California Cancer Center with which Stanford has had a long-standing, scientifically productive relationship under a formal affiliation agreement. The CCSG proposal is built upon institutional strengths in technology development, particularly in the fields of imaging, biotechnology, informatics, and chemical engineering. The integration of these research areas into the fields of cancer biology, immunology, genetics and stem cell biology in the development of new approaches to cancer prevention, diagnosis and treatment is the distinguishing feature of this Cancer Center. Ten programs cover the areas of basic, translational/clinical, and population science research in cancer (Cancer Biology, Radiation Biology, Cancer Stem Cells, Cancer Imaging and Early Detection, Molecular Therapeutics, Lymphoma and Hodgkin Disease, Cancer Immunology and Immunotherapy, Hematopoietic Cell Transplantation and Immune Reconstitution, Cancer Epidemiology, and Cancer Prevention and Control). Eleven Shared Resources support the basic and translational/clinical investigation that is carried out in the Center. Based on current NCI base funding of $36 million and with $58 million in other NIH support and $16 million in other peer-reviewed cancer-relevant funding, the Center is requesting $5.3 million in direct costs to support its activities. With the advent of two new buildings for basic and translational research, new recruitment, and increased collaborative interactions, the Center is poised to make significant contributions to cancer research in the new funding period.