Stanford University Cancer Center

斯坦福大学癌症中心

• 批准号: 9022012
• 负责人: BEVERLY S. MITCHELL
• 金额: $ 224.92万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-04 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9022012
• 关键词: Agreement; Applications Grants; Area; Basic Science; Biotechnology; California; Cancer Biology; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Immunology Science; Chemical Engineering; Clinical; Comprehensive Cancer Center; Development; Diagnosis; Direct Costs; Early Diagnosis; Engineering; Funding; Genetic; Hodgkin Disease; Humanities; Image; Immune; Immunology; Informatics; Laws; Lymphoma; Malignant Neoplasms; Medicine; Molecular; National Cancer Institute; Peer Review; Population Sciences; Radiobiology; Research; Resource Sharing; Schools; Science; Therapeutic; Translational Research; United States National Institutes of Health; Universities; anticancer research; base; cancer epidemiology; cancer imaging; cancer immunotherapy; cancer prevention; cancer stem cell; clinical investigation; hematopoietic cell transplantation; member; novel strategies; programs; reconstitution; stem cell biology; technology development

DESCRIPTION (provided by applicant): The Stanford Cancer Center is applying to the National Cancer Institute (NCI) for five years of funding of a Cancer Center Support Grant (CCSG) and for designation as a Comprehensive Cancer Center. Over the past three years, the Cancer Center has grown from 260 to 311 members representing four Schools within Stanford University (Medicine, Engineering, Humanities and Sciences and Law) and the Northern California Cancer Center with which Stanford has had a long-standing, scientifically productive relationship under a formal affiliation agreement. The CCSG proposal is built upon institutional strengths in technology development, particularly in the fields of imaging, biotechnology, informatics, and chemical engineering. The integration of these research areas into the fields of cancer biology, immunology, genetics and stem cell biology in the development of new approaches to cancer prevention, diagnosis and treatment is the distinguishing feature of this Cancer Center. Ten programs cover the areas of basic, translational/clinical, and population science research in cancer (Cancer Biology, Radiation Biology, Cancer Stem Cells, Cancer Imaging and Early Detection, Molecular Therapeutics, Lymphoma and Hodgkin Disease, Cancer Immunology and Immunotherapy, Hematopoietic Cell Transplantation and Immune Reconstitution, Cancer Epidemiology, and Cancer Prevention and Control). Eleven Shared Resources support the basic and translational/clinical investigation that is carried out in the Center. Based on current NCI base funding of $36 million and with $58 million in other NIH support and $16 million in other peer-reviewed cancer-relevant funding, the Center is requesting $5.3 million in direct costs to support its activities. With the advent of two new buildings for basic and translational research, new recruitment, and increased collaborative interactions, the Center is poised to make significant contributions to cancer research in the new funding period.

描述（由申请人提供）：斯坦福癌症中心正在向美国国家癌症研究所（NCI）申请五年的癌症中心支持资助（CCSG），并被指定为综合癌症中心。在过去的三年里，癌症中心的成员从260人增长到311人，代表了斯坦福大学的四个学院（医学、工程、人文科学和法律）以及北加州癌症中心，斯坦福大学与北加州癌症中心在正式的合作协议下有着长期的、科学的、富有成效的关系。CCSG的建议建立在技术发展的体制优势之上，特别是在成像、生物技术、信息学和化学工程领域。将这些研究领域整合到癌症生物学、免疫学、遗传学和干细胞生物学领域，以开发癌症预防、诊断和治疗的新方法，是该癌症中心的显著特色。10个项目涵盖癌症的基础、转化/临床和人口科学研究领域（癌症生物学、放射生物学、癌症干细胞、癌症成像和早期检测、分子治疗、淋巴瘤和霍奇金病、癌症免疫学和免疫治疗、造血细胞移植和免疫重建、癌症流行病学和癌症预防与控制）。11个共享资源支持中心开展的基础和转化/临床研究。基于目前NCI的3600万美元基础资金，加上其他NIH支持的5800万美元和其他同行评审的癌症相关资金1600万美元，该中心要求530万美元的直接费用来支持其活动。随着基础研究和转化研究两幢新大楼的落成，新招募人员，以及合作互动的增加，中心准备在新的资助期内为癌症研究做出重大贡献。