Computational and mathematical modeling of biomedical systems

描述（由申请人提供）：该计划将通过博士前水平的跨学科培训，为科学家在医学重要生物系统的计算分析和数学建模方面的研究事业做好准备。亚利桑那大学以其完善的跨学科研究生课程体系和跨部门合作的传统而闻名，为这种培训提供了非常合适的环境。17个培训教师和两个助理教师在多个部门和跨学科的研究生课程的任命提供了三个广泛的领域的实力：分子动力学;细胞过程;生理学和病理生理学。学生将主要来自应用数学跨学科课程和跨学科生物化学和分子与细胞生物学课程。来自其他研究生课程的合格学生也将有资格。在大多数情况下，学生将在研究生培训的第二年开始获得支持。学员将追求自己的研究生课程的课程要求，并将，此外，采取研究生课程，生物信息学，生物统计学和数学建模量身定制，以他们不同的科学背景。学员将参加每周一次的生物数学座谈会，该座谈会已经持续了十多年，并促进学员与主要具有数学或计算背景的教师以及那些具有强大生物学培训的教师之间的对话。实习生将与顾问进行博士研究，他们的研究，无论是理论还是实验，都强调理论方法在生物医学问题中的应用。在适当的情况下，将任命一名共同顾问，为主要顾问提供补充专业知识。参加该计划的学员不仅将接受相关领域的研究培训，还将发展跨传统学科界限的沟通和合作能力，并与具有互补专业知识的研究人员合作。生物医学科学的许多领域都迫切需要具有这种技能的研究人员，这些领域需要复杂的理论方法才能取得进一步的进展。相关性：在生物医学科学的许多领域，为了取得进一步的进展，复杂的理论方法是必要的。该计划将通过博士前水平的跨学科培训，为科学家在医学重要生物系统的计算分析和数学建模方面的研究事业做好准备。

DESCRIPTION (provided by applicant): This program will prepare scientists for research careers in the computational analysis and mathematical modeling of medically significant biological systems through interdisciplinary training at the predoctoral level. Noted for its well-established system of interdisciplinary graduate programs and for its tradition of collaborations across departmental boundaries, the University of Arizona provides a highly suitable environment for such training. Seventeen training faculty and two associate faculty with appointments in multiple departments and interdisciplinary graduate programs provide strength in three broad areas: molecular dynamics; cellular processes; physiology and pathophysiology. Students will be drawn primarily from the interdisciplinary Program in Applied Mathematics and the cross-disciplinary Biochemistry and Molecular & Cellular Biology Program. Qualified students from other graduate programs will also be eligible. In most cases, students will receive support starting in their second year of graduate training. Trainees will pursue the coursework requirements of their own graduate programs and will, in addition, take graduate courses in bioinformatics, biostatistics and mathematical modeling tailored to their diverse scientific backgrounds. Trainees will take part in a weekly biomathematics colloquium that has been running continuously for more than a decade and promotes dialog between trainees and faculty with primarily mathematical or computational backgrounds and those with strong biological training. Trainees will carry out doctoral research with advisors whose research, whether theoretical or experimental, emphasizes application of theoretical approaches to biomedical problems. Where appropriate, a co-advisor will be appointed to provide complementary expertise to that of the primary advisor. Trainees participating in this program will not only receive research training in relevant areas, but will also develop the ability to communicate and collaborate across traditional disciplinary boundaries and to work with researchers with complementary expertise. Researchers with such skills are critically needed in many areas of biomedical science in which sophisticated theoretical approaches are necessary in order to achieve further progress. Relevance: In many areas of biomedical science, sophisticated theoretical approaches are necessary in order to achieve further progress. This program will prepare scientists for research careers in the computational analysis and mathematical modeling of medically significant biological systems through interdisciplinary training at the predoctoral level.