Body-oriented Therapy for Womens Substance Use Disorder Treatment

女性药物滥用障碍治疗的身体导向疗法

• 批准号: 8437077
• 负责人: CYNTHIA J PRICE
• 金额: $ 50.84万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8437077
• 关键词: Address; Affect; Aftercare; Alcohol dependence; Alcohol or Other Drugs use; Alcohols; Attention; Awareness; Behavior Control; Behavioral; Beryllium; Biological Markers; Brain; Clinical Research; Communities; Dependence; Disease; Dissociation; Drug Addiction; Drug usage; Economics; Education; Effectiveness; Emotional; Employment; Enrollment; Female; Funding; Gender; Goals; Health; Health education; Illicit Drugs; Imprisonment; Individual; Institute of Medicine (U.S.); Learning; Legal; Longitudinal Studies; Manuals; Measures; Mediating; Mediator of activation protein; Medical; Mental Health; Mind-Body Intervention; National Institute of Drug Abuse; Outcome; Outpatients; Patient Self-Report; Patients; Process; Psychophysiology; Public Health; Randomized; Randomized Clinical Trials; Recruitment Activity; Regulation; Relapse; Reporting; Research; Risk; Self Care; Sensory; Societies; Staging; Strategic Planning; Stress; Stroke; Substance Use Disorder; Surveys; Testing; Therapeutic Intervention; Time; Training; Trauma; Treatment Efficacy; Treatment outcome; United States National Institutes of Health; Woman; Women' s Health; addiction; aged; base; body-mind; cost; design; disorder later incidence prevention; drug addict; economic outcome; efficacy testing; emotion regulation; follow-up; improved; innovation; meetings; men; mindfulness; novel; physical conditioning; post intervention; prevent; programs; public health relevance; reduced substance use; sex; skills; substance abuse treatment; therapy development; tool; treatment as usual

DESCRIPTION (provided by applicant): The long-term objective of this study is to improve women's substance use disorder (SUD) treatment. The immediate project goal is to test the efficacy of an innovative mind-body intervention, Mindful Awareness in Body-Oriented Therapy (MABT) to reduce substance use relapse among women in SUD treatment. A novel mind-body approach, MABT combines a hands-on (manual) approach with mind-body psycho-education approaches of interoceptive training and mindfulness to develop somatically-based self-care skills and to facilitate emotion regulation. A three-group, randomized clinical trial using repeate measures, this project will enroll and randomize 225 women to one of three groups, MABT + Treatment-as-usual (TAU) (n=75), TAU only (n=75), and Women's Health Education (WHE) + TAU (to control for time and attention) (n=75). Study conditions will be compared at baseline, post-intervention, and at 6 and 12 month follow-up. The primary aim is to test the hypothesis that MABT will result in reduced substance use and related health outcomes compared to TAU and to WHE+ TAU at 12 month follow-up. The second aim is to examine hypothesized underlying mechanisms of MABT. The third aim is to explore an interoceptive biomarker as a predictor of treatment outcome. Female outpatients in two diverse community treatment facilities, serving racially diverse patients, will be recruited for study participation. This stud builds on promising preliminary evidence of MABT feasibility and acceptability in substance use disorder treatment for women, and addresses the need for more clinical research aimed at improving SUD treatment outcomes for women.

描述（由申请人提供）：本研究的长期目标是改善女性物质使用障碍（SUD）的治疗。该项目的直接目标是测试一种创新的身心干预，正念意识在身体导向治疗（MABT）中减少女性在SUD治疗中的药物使用复发的有效性。作为一种新颖的身心方法，MABT结合了动手（手工）方法和内感受训练和正念的身心心理教育方法，以发展基于身体的自我照顾技能并促进情绪调节。这是一项采用重复测量方法的三组随机临床试验，该项目将招募并随机将225名妇女分为三组，MABT +常规治疗（TAU） （n=75），仅TAU （n=75）和妇女健康教育(WHE) + TAU（以控制时间和注意力）（n=75）。研究条件将在基线、干预后、6个月和12个月随访时进行比较。主要目的是在12个月的随访中验证与TAU和WHE+ TAU相比，MABT会导致物质使用减少和相关健康结果的假设。第二个目的是检验假设的MABT的潜在机制。第三个目的是探索作为治疗结果预测因子的内感受性生物标志物。将招募两个不同社区治疗机构的女性门诊患者参与研究，为不同种族的患者提供服务。本研究建立在MABT在女性药物使用障碍治疗中的可行性和可接受性的有希望的初步证据之上，并提出了更多旨在改善女性药物使用障碍治疗结果的临床研究的需求。