女性药物滥用障碍治疗的身体导向疗法-猫眼课题宝

女性药物滥用障碍治疗的身体导向疗法

批准号：

8733140

负责人：

CYNTHIA J PRICE

金额：

$45.61万

依托单位：

UNIVERSITY OF WASHINGTON

依托单位国家：

美国

项目类别：

财政年份：

2013

资助国家：

美国

项目状态：

已结题

起止时间：

2013-09-15 至 2017-06-30

来源：

https://reporter.nih.gov/project-details/8733140

关键词：

Address Affect Aftercare Alcohol dependence Alcohol or Other Drugs use Alcohols Attention Awareness Behavior Control Behavioral Beryllium Biological Markers Brain Clinical Research Communities Dependence Dissociation Drug Addiction Drug usage Economics Education Effectiveness Emotional Employment Enrollment Female Funding Gender Goals Health Health education Illicit Drugs Imprisonment Individual Institute of Medicine (U.S.)Learning Legal Longitudinal Studies Manuals Measures Mediating Mediator of activation protein Medical Mental Health Mind-Body Intervention National Institute of Drug Abuse Outcome Outpatients Patient Self-Report Patients Process Psychophysiology Public Health Randomized Randomized Clinical Trials Recruitment Activity Regulation Relapse Reporting Research Risk Self Care Sensory Societies Staging Strategic Planning Stress Stroke Substance Use Disorder Surveys Testing Therapeutic Intervention Time Training Trauma Treatment Efficacy Treatment outcome United States National Institutes of Health Woman Women&apos s Health addiction aged base body-mind cost design disorder later incidence prevention drug addict dual diagnosis economic outcome efficacy testing emotion regulation follow-up improved innovation meetings men mindfulness novel physical conditioning post intervention prevent programs public health relevance reduced substance use sex skills substance abuse treatment therapy development tool treatment as usual

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中文摘要

翻译

描述（由申请人提供）：本研究的长期目标是改善女性物质使用障碍（SUD）的治疗。该项目的近期目标是测试创新的身心干预措施——身体导向疗法中的正念意识（MABT）的功效，以减少接受 SUD 治疗的女性药物滥用复发。 MABT 是一种新颖的身心方法，将动手方法与内感受训练和正念的身心心理教育方法相结合，以培养基于躯体的自我护理技能并促进情绪调节。该项目是一项使用重复措施的三组随机临床试验，将招募 225 名女性并将其随机分为三组：MABT 照常治疗 (TAU) (n=75)、仅 TAU (n=75) 和妇女健康教育 (WHE) TAU（控制时间和注意力）(n=75)。将在基线、干预后以及 6 个月和 12 个月的随访时比较研究条件。主要目的是检验以下假设：在 12 个月的随访中，与 TAU 和 WHE TAU 相比，MABT 会减少物质使用和相关健康结果。第二个目标是检查假设的 MABT 潜在机制。第三个目标是探索内感受生物标志物作为治疗结果的预测因子。将招募两个不同社区治疗设施中为不同种族患者提供服务的女性门诊患者参与研究。这项研究建立在 MABT 在女性物质使用障碍治疗中的可行性和可接受性的有希望的初步证据的基础上，并解决了旨在改善女性 SUD 治疗结果的更多临床研究的需要。

英文摘要

DESCRIPTION (provided by applicant): The long-term objective of this study is to improve women's substance use disorder (SUD) treatment. The immediate project goal is to test the efficacy of an innovative mind-body intervention, Mindful Awareness in Body-Oriented Therapy (MABT) to reduce substance use relapse among women in SUD treatment. A novel mind-body approach, MABT combines a hands-on (manual) approach with mind-body psycho-education approaches of interoceptive training and mindfulness to develop somatically-based self-care skills and to facilitate emotion regulation. A three-group, randomized clinical trial using repeate measures, this project will enroll and randomize 225 women to one of three groups, MABT + Treatment-as-usual (TAU) (n=75), TAU only (n=75), and Women's Health Education (WHE) + TAU (to control for time and attention) (n=75). Study conditions will be compared at baseline, post-intervention, and at 6 and 12 month follow-up. The primary aim is to test the hypothesis that MABT will result in reduced substance use and related health outcomes compared to TAU and to WHE+ TAU at 12 month follow-up. The second aim is to examine hypothesized underlying mechanisms of MABT. The third aim is to explore an interoceptive biomarker as a predictor of treatment outcome. Female outpatients in two diverse community treatment facilities, serving racially diverse patients, will be recruited for study participation. This stud builds on promising preliminary evidence of MABT feasibility and acceptability in substance use disorder treatment for women, and addresses the need for more clinical research aimed at improving SUD treatment outcomes for women.

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