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中文摘要
翻译
约翰霍普金斯大学自1955年以来一直是ECOG的成员。我们的主要目标是将约翰霍普金斯大学试点的创新临床研究方案和实验室相关科学带到集团进一步发展。与此同时,我们的教师担任研究主席和实验室联合主席,疾病和模式导向委员会主席的领导角色。
英文摘要
Johns Hopkins has been a member of ECOG since 1955. Our primary goal is to bring innovative clinical research protocols and laboratory correlative science piloted at Johns Hopkins to the Group for further development. In conjunction with this, our faculty serve in leadership roles as study chairs and laboratory co-chairs, disease and modality-oriented committee chairs. The specific aims are: 1) to continue to provide scientific leadership in the disease-oriented committees: Breast, Thoracic, Head and Neck, Genitourinary, Brain Tumor Working Group, Lymphoma, Leukemia; 2) to continue to expand our involvement in the disease and modality committees: Gastrointestinal, Myeloma, Pharmacology and Drug Development; to bring translational research correlates, cell biology and molecular biology into clinical protocols for all stages of disease; 4) to continue to expand accrual, and to maintain excellent performance in data quality. These goals will be accomplished through the mission of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: to provide a multidisciplinary approach to the study of cancer that will result in improved means for prevention, diagnosis, and treatment. The Center has achieved excellence in translational research with the awarding of seven SPORE grants (cervix, lymphoma, G-l cancer, prostate, breast, lung, head and neck). In addition, early clinical trials of new drugs are conducted under the NCI phase I contract (since 1982). The Early Therapeutics Development with Phase II Emphasis grants allow the development of novel phase II and phase III concepts which the Cancer Center faculty bring to ECOG with appropriate laboratory science correlative studies. The expansion of Center facilities allows the development of new clinical prograins, the recruitment of new faculty, furthering committee involvement and clinical trial accrual.
期刊论文(18)
专著(0)
科研奖励(0)
会议论文
DOI: --
发表时间: 1993
期刊: Journal of the National Cancer Institute. Monographs
影响因子: --
作者: [A. Forastiere;D. Neuberg;S. Taylor;R. Deconti;G. Adams]
通讯作者: A. Forastiere;D. Neuberg;S. Taylor;R. Deconti;G. Adams
DOI: 10.1371/journal.pone.0207145
发表时间: 2018
期刊: PloS one
影响因子: 3.7
作者: [Donadio A, Whitehead K, Gonzalez F, Wilhelm E, Formica D, Meek J, Fabrizi L, Burdet E]
通讯作者: Burdet E
A phase II study of Didemnin B (NSC 325319) in advanced malignant melanoma: an Eastern Cooperative Oncology Group study (PB687).
Didemnin B (NSC 325319) 治疗晚期恶性黑色素瘤的 II 期研究:东部肿瘤合作组研究 (PB687)。
DOI: 10.1023/a:1006110431250
发表时间: 1998
期刊: Investigational new drugs
影响因子: 3.4
作者: [Hochster,H, Oratz,R, Ettinger,DS, Borden,E]
通讯作者: Borden,E
DOI: 10.1002/(sici)1097-0142(19980601)82:11
发表时间: 1998-06-01
期刊: CANCER
影响因子: 6.2
作者: [Forastiere, AA, Shank, D, Adams, G]
通讯作者: Adams, G
10
    EASTERN COOPERATIVE ONCOLOGY GROUP
    • 批准号:
      2414073
    • 项目类别:
    • 资助金额:
      $20.31万
    • 财政年份:
      1978
    • 负责人:
      ARLENE ANN FORASTIERE
    • 依托单位:
    Eastern Cooperative Oncology Group
    • 批准号:
      6904489
    • 项目类别:
    • 资助金额:
      $30.37万
    • 财政年份:
      1978
    • 负责人:
      ARLENE ANN FORASTIERE
    • 依托单位:
    EASTERN COOPERATIVE ONCOLOGY GROUP
    • 批准号:
      2086443
    • 项目类别:
    • 资助金额:
      $16.3万
    • 财政年份:
      1978
    • 负责人:
      ARLENE ANN FORASTIERE
    • 依托单位:
    EASTERN COOPERATIVE ONCOLOGY GROUP
    • 批准号:
      2086445
    • 项目类别:
    • 资助金额:
      $21.36万
    • 财政年份:
      1978
    • 负责人:
      ARLENE ANN FORASTIERE
    • 依托单位:
    海外基金