Project 3: Adolescent smoking: Vulnerability to Tobacco Use and Market p265-296

项目 3：青少年吸烟：烟草使用和市场的脆弱性 p265-296

• 批准号: 8595436
• 负责人: MARY ANN PENTZ
• 金额: $ 81.61万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-19 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8595436
• 关键词: 18 year old; Address; Adolescence; Adolescent; Adult; Age; Age-Years; Attitude; Belief; California; Characteristics; Child health care; Childhood; Chronic; Cigarette; Cohort Studies; Communication; Communities; Data; Electronics; Future; Health; Hispanics; Home environment; Industry; Instruction; Interview; Life; Marketing; Metric; Modeling; Nature; Neighborhoods; Nicotine Dependence; Not Hispanic or Latino; Participant; Pattern; Perception; Phenotype; Predisposition; Prevention; Process; Recruitment Activity; Regulation; Research; Research Priority; Risk; Role; Route; Sales; Sampling; Schools; Science; Smoker; Smoking; Staging; Statistical Models; Tobacco; Tobacco Industry; Tobacco use; Vulnerable Populations; Work; adolescent smoking; base; cigarette smoking; density; follow-up; high risk; high school; non-smoker; novel; response; smoking cessation; social; tobacco advertising; young adult

Early initiation of smoking and rapid progression during the key adolescent and young adult period predict chronic and addicted smoking in adult life and high risk for health consequences. However, there has been little research on how adolescent smoking trajectories relate to future vulnerability to industry marketing and emerging products intended to sustain nicotine addiction. This project addresses the hypothesis that the early course of cigarette smokino is a key determinant of future nicotine dependence and vulnerability to point-of-sale and electronic marketing, resulting in future use of new non-cigarette products and polv-tobacco use. These questions are addressed using data from over 12,000 largely Hispanic and non-Hispanic White participants recruited from Southern California schools into the Children's Health Study cohort between 1993 and 2002. Smoking data have been collected yearly through high school graduation at age 18. Using these data and state-of-the-art statistical modeling, adolescent cigarette smoking trajectories will be characterized based on initiation and progression patterns. Associations of these trajectories with neighborhood and community environmental, demographic and social factors, and with marketing exposure, based on tobacco retailer proximity and density at home, school and a novel route to school metric, will be assessed. Samples of smokers and at-risk non-smokers in the younger wave of recruitment currently 17-18 years of age (N=600) and of smokers from eariier waves now 26-36 years of age (N=450) will be re-interviewed and followed prospectively to assess the relationships of early life smoking trajectory with tobacco product perception, attitudes and beliefs, persistence of use and difficulty quitting smoking. Specific types of tobacco marketing at point-of-sale, through electronic and social media, and interpersonal influences that amplify the risk of different trajectories of childhood tobacco use will be identified. A hierarchical modeling approach will integrate information on early life smoking trajectory, marketing, perceptions, attitudes and beliefs across life stages and over follow-up to elucidate the role of each in use of new tobacco products. The study will yield refined information on nature and characteristics of early life smoking phenotype trajectories and on response to marketing relevant to regulation and prevention among vulnerable populations. Further, it will clarify how eariy-life cigarette smoking serves as a gateway process to other forms of tobacco product use, which could be amplified by tobacco marketing. It addresses FDA research priorities: vulnerability, perceptions, attitudes and beliefs, understanding new product use, and marketing. RELEVANCE (See instructions): The study will examine vulnerability, based on early life smoking profiles, to new and poly-tobacco product use, marketing and nicotine dependence into adult life. FDA regulatory research priorities addressed include (a) the diversity of tobacco product use and impact of different types of marketing on perceptions, attitudes and beliefs, and on products used; (b) understanding communication about tobacco products; and (c) understanding marketing of new tobacco products by social and other electronic media and at point-of-sale;

青少年和青年关键时期的早期开始吸烟和快速进展预示着 成人生活中长期吸烟和成瘾，对健康造成的风险很高。然而，已经有 关于青少年吸烟轨迹与未来易受行业营销和影响的脆弱性之间的关系的研究很少 旨在维持尼古丁成瘾的新兴产品。该项目提出了这样一个假设： 吸烟的早期过程是未来尼古丁依赖和易感性的关键决定因素 销售点和电子营销，导致未来使用新的非卷烟产品和多用途烟草 使用。这些问题是通过超过 12,000 名主要是西班牙裔和非西班牙裔白人的数据得到解决的 1993 年期间从南加州学校招募到儿童健康研究队列的参与者 和 2002 年。从 18 岁高中毕业开始，每年都会收集吸烟数据。使用这些数据 数据和最先进的统计模型，将描述青少年吸烟轨迹 基于启动和进展模式。这些轨迹与邻域和 社区环境、人口和社会因素，以及基于烟草的营销曝光 将评估零售商在家里、学校的距离和密度以及到学校的新路线指标。样品 目前 17-18 岁的年轻招募浪潮中吸烟者和高危非吸烟者的比例 (N=600) 以及现在 26-36 岁的早期吸烟者 (N=450) 将被重新访谈和跟踪 前瞻性地评估早期吸烟轨迹与烟草产品认知的关系， 态度和信念、持续使用和戒烟困难。烟草营销的具体类型 在销售点，通过电子和社交媒体以及人际影响，会放大风险 将确定儿童烟草使用的不同轨迹。分层建模方法将 整合有关生命早期吸烟轨迹、营销、认知、态度和信仰的信息 阶段和后续行动，以阐明每个阶段在新型烟草产品使用中的作用。该研究将产生 有关早期吸烟表型轨迹的性质和特征的精炼信息 对与弱势群体的监管和预防相关的营销的反应。此外，还将 澄清早期吸烟如何成为其他形式烟草产品使用的门户过程， 烟草营销可以放大这种影响。它解决了 FDA 的研究重点：脆弱性、 观念、态度和信念，了解新产品的使用和营销。 相关性（参见说明）： 该研究将根据早期吸烟情况，研究对新的复合烟草产品的脆弱性 使用、营销和成年生活中的尼古丁依赖。 FDA 监管研究重点包括 (a) 烟草制品使用的多样性以及不同类型营销对认知、态度的影响 和信仰以及所使用的产品； (b) 了解有关烟草制品的沟通；和（三） 了解社交媒体和其他电子媒体以及销售点对新型烟草产品的营销；