Research Translation Core

项目总结(见说明)： 自然和人为污染物对人类和生态系统健康造成不利影响。生物医学研究的知识除非以可理解的方式有效地传达给卫生专业人员、政府监管机构、行业和其他终端用户或利益攸关方，否则不能最大限度地利用这些知识。我们假设，研究科学家和研究成果的利益相关者之间的有效双向沟通将改善科学家正在进行的研究，为监管机构提供更相关的信息，提高这项研究的整体效益，并最终导致对现有环境问题的最佳可能解决方案。密歇根州立大学(MSU)超级基金研究计划(SRP)中心专注于二恶英及其类似化合物(DLC)的毒理学和环境命运，这些化合物已被确定为密歇根州三城市(萨吉诺、米德兰、湾城)地区的环境污染物。密歇根州立大学SRP中心研究翻译核心(RTC)将成为密歇根州立大学SRP中心和主要利益攸关方之间传播信息、技术转让和教育活动的双向桥梁。具体地说，我们的利益攸关方是州政府机构，包括密歇根州环境质量局(MDEQ)和密歇根州农业部(MDARD)，联邦政府机构，包括美国环境保护局(USEPA)地区5和有毒物质和疾病登记局(ATSDR)，以及行业，如沉积物管理工作组(SMWG)。归根结底，最重要的利益相关者是存在环境污染的社区的居民，因此，我们将社区医院的卫生专业人员确定为新的利益相关者，因为他们可以成为研究转化的关键渠道。卫生专业人员的培训将在密歇根州立大学人类医学院的弗林特和米德兰地区校区进行。上述利益相关者联盟为来自政府、工业和学术界的科学家提供了一个独特的机会，以合作解决密歇根州围绕二恶英和DLC的复杂环境问题。为此，将通过以下方式检验上述假设：(A)使用成熟的通信工具；(B)与政府和工业界结成伙伴关系；(C)利用新机制转让技术；(D)提供教育资源。

PROJECT SUMMARY (See instructions): Naturally occurring and anthropogenic pollutants adversely affect human and ecosystem health. Knowledge from biomedical research is not utilized to its maximum potential unless it is effectively communicated in an understandable manner to health professionals, government regulatory agencies, industry and other end users, or stakeholders. We hypothesize that effective bidirectional communication between research scientists and stakeholders of research findings will improve the research being conducted by scientists provide more relevant information for regulatory agencies, enhance the overall benefits of this research, and ultimately lead to the best possible solutions to existing environmental problems. The Michigan State University (MSU) Superfund Research Program (SRP) Center focuses on the toxicology and environmental fate of dioxin and dioxin-like compounds (DLC), which have been identified as environmental contaminants in the Tri-Cities (Saginaw, Midland, Bay City) area in Michigan. The MSU SRP Center Research Translation Core (RTC) will serve as a bidirectional bridge for disseminating information, technology transfer and educational activities between the MSU SRP Center and key stakeholders. Specifically, our stakeholders are State government agencies, including Michigan Department Environment Quality (MDEQ) and Michigan Department of Agriculture Michigan Department of Agriculture and Rural Development (MDARD), Federal government agencies, including the United States Environmental Protection Agency (USEPA) Region 5 and the Agency for Toxic Substances and Disease Registry (ATSDR), and industry, such as the Sediment Management Working Group (SMWG). Ultimately, the most important stakeholders are the residents in communities in which environmental contamination exists and therefore, we have identified health professionals in community-based hospitals as novel stakeholders since they can be critical conduits of research translation. Training of health professionals will occur at the Flint and Midland Regional Campuses of the MSU College of Human Medicine. This aforementioned consortium of stakeholders provides a unique opportunity for scientists from government, industry and academia to collaborate on solutions to complex environmental problems surrounding dioxin and DLC in the State of Michigan. Toward this end, the above stated hypothesis will be tested by: (a) using well-established communication tools; (b) partnering with government and industry; (c) transferring technology using novel mechanisms; and (d) providing educational resources.