Methods Core

方法核心将通过威斯康星大学麦迪逊分校、宾夕法尼亚州立大学和华盛顿大学具有方法和统计专业知识的研究人员的合作和贡献，在支持中心范围的科学目标方面发挥关键作用。具体目标包括：具体目标1：进行数据分析，为中心所有项目提供测量和数据分析咨询。拟议的中心拨款将支持三个主要研究项目以及试点项目。方法核心调查员将提供专门的方法和统计专业知识，以支持这些不同的项目，包括 就研究设计、评估、参与者的招募和保留、干预措施的实施、数据收集和数据分析进行咨询。具体目标2：为初级调查人员提供方法和统计支持。方法核心调查员将在研究设计、方法、力量分析和数据分析等方面为初级调查员提供帮助。此外，还将协助初级调查人员编写资助申请的方法章节和提交同行审查期刊的文章。具体目标3：管理所有中心数据的集中数据库。这三个主要研究项目将产生大量数据，这些数据需要高效和安全地收集和存储。威斯康星大学麦迪逊烟草研究和干预中心(UWCTRI)的调查人员和工作人员将建立和维护所有中心数据的安全集中数据库，并负责为数据分析准备数据。具体目标4：为整个中心安排和提供有关方法和统计专题的教育和培训。方法核心调查人员和工作人员将 组织和举办研讨会，提供个人指导，并使用其他机制为中心赠款工作人员提供与中心相关研究和活动相关的方法和统计主题的教育和培训。

The Methods Core will play a critical role in supporting Center-wide scientific objectives through collaboration and contributions of UW-Madison, Penn State, and University of Washington investigators with methodological and statistical expertise. Specific aims include: Specific Aim 1: To perform data analysis and to provide consultation on measurement and data analysis for all Center projects. The proposed Center grant will support the three main research projects as well as pilot projects. Methods Core investigators will provide specialized methodological and statistical expertise in support of these various projects including consultation on study design, assessment, recruitment and retention of participants, intervention delivery, data collection, and data analysis. Specific Aim 2: To provide methodological and statistical support for junior investigators. Methods Core investigators will provide assistance to junior investigators in terms of study design, methods, power analysis, and data analysis. In addition, assistance will be provided to junior investigators in preparing methods sections for funding applications and articles to submit to peer-review journals. Specific Aim 3: To manage a centralized database of all Center data. The three main research projects will generate a considerable amount of data that will need to be efficiently and securely collected and stored. Investigators and staff at the UW-Madison Center for Tobacco Research and Intervention (UWCTRI) will establish and maintain a secure centralized database of all Center data and will be responsible for preparing data for data analysis. Specific Aim 4: To arrange and provide education and training on methodological and statistical topics for the entire Center. Methodology Core investigators and staff will organize and conduct workshops, provide individual mentorship, and use other mechanisms to provide education and training for Center grant staff on methodological and statistical topics relevant to Center-related studies and activities.