Core 2: Data Analysis Core (Analysis Core)

核心2：数据分析核心（Analysis Core）

• 批准号: 10415923
• 负责人: DANIEL M BOLT
• 金额: $ 20.22万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415923
• 关键词: Address; Biometry; Chronic Care; Clinical; Collaborations; Collection; Combination Medication; Consult; Continuity of Patient Care; Cost Effectiveness Analysis; Data; Data Analyses; Data Set; Decision Analysis; Decision Making; Development; Effectiveness; Electronic Health Record; Ensure; Evaluation; Experimental Designs; Goals; Health system; Healthcare; Healthcare Systems; Intervention; Intervention Studies; Knowledge; Linear Regressions; Logistic Regressions; Mediation; Methodology; Methods; Modeling; Monitor; Nicotine; Outcome; Phase; Population; Preparation; Primary Health Care; Procedures; Program Research Project Grants; Reach Effectiveness Adoption Implementation and Maintenance; Readiness; Research; Research Methodology; Research Personnel; Research Project Grants; Resource Allocation; Role; Services; Smoker; Smoking; Smoking Cessation Intervention; Statistical Data Interpretation; System; Techniques; Time; Tobacco; Treatment Cost; Treatment outcome; Universities; Wisconsin; base; cost effectiveness; data integration; data management; design; experience; experimental study; future implementation; health care settings; implementation cost; implementation intervention; innovation; member; multiphase optimization strategy; nicotine patch; nicotine replacement; novel; operation; primary outcome; programs; screening; smoking cessation; smoking intervention; smoking prevalence; therapy development; treatment optimization; treatment program; treatment strategy; varenicline

Project Summary The Data Analysis Core supports the scientific objectives of the four research projects of this Research Program Project primarily through data management and statistical analysis services. In this role, and through collaboration with Design and Optimization Core and other Program Project investigators, the Data Analysis Core will manage all Program Project data and will apply and interpret a variety of statistical techniques for analyzing research project data to support the development of an optimized healthcare system smoking program (the Comprehensive Chronic Care Smoking Treatment Program: CCCSTOP). Services provided by the Analysis Core include: 1) cleaning, preparing, documenting, and sharing research project data for subsequent statistical analysis; 2) conducting statistical analyses to address primary and secondary aims associated with the four research projects, including the modeling of key binary and continuous outcomes in relation to the main and interaction effects of studied intervention components using approaches such as linear and logistic regression models; 3) development and application of statistical techniques to synthesize results across multiple outcomes, particularly in the screening stages of the Multiphase Optimization Strategy (MOST) approach; 4) implementation of cost-effectiveness analyses that will permit evaluation of treatment outcomes in relation to the cost of treatment; 5) conducting analyses of qualitative and quantitative data to assist Implementation Project investigators in the evaluation of intervention Reach, Efficacy, Adoption, Implementation, and Maintenance (RE-AIM model); and 6) coordinating and consulting with Project and Core Leaders to develop analytic plans that ensure that analyses address clinically and substantively important research goals and to assist in interpretation of obtained results. Members of the Data Analysis Core will meet regularly with investigators to ensure the scientific integrity of the research plan implementation, to monitor and discuss overall progress as well as specific project needs, and to make decisions related to prioritization and allocation of resources provided by the Data Analysis Core.

项目摘要 数据分析核心支持本研究四个研究项目的科学目标 方案项目主要通过数据管理和统计分析服务。在这一角色中，并通过 与设计和优化核心及其他计划项目调查人员合作，数据分析 CORE将管理所有计划项目数据，并将应用和解释各种统计技术 分析研究项目数据以支持开发优化的医疗保健系统吸烟 方案(全面慢性护理吸烟治疗方案：CCCSTOP)。提供的服务由 分析核心包括：1)清理、准备、记录和共享研究项目数据 随后的统计分析；2)进行统计分析，以解决主要和次要目标 与四个研究项目有关，包括对#年关键的二元和连续成果进行建模 使用诸如线性等方法与所研究的干预成分的主要作用和交互作用的关系 和Logistic回归模型；3)发展和应用统计技术来综合结果 跨越多个结果，特别是在多阶段优化战略(MOST)的筛选阶段 方法；4)执行成本效益分析，以便能够评价#年的治疗结果 与治疗费用的关系；5)对定性和定量数据进行分析，以帮助 实施项目调查员在评估干预范围、有效性、采纳度、 实施和维护(RE-AIM模式)；以及6)与项目和核心协调和咨询 领导制定分析计划，确保分析解决临床和实质上的重要问题 研究目标，并协助解释已取得的结果。数据分析核心的成员将举行会议 定期与调查人员合作，确保研究计划实施的科学完整性，监督和 讨论总体进度和具体的项目需求，并做出与优先顺序和 分配数据分析核心提供的资源。