Neural Development of Deductive Reasoning

演绎推理的神经发展

• 批准号: 8442270
• 负责人: James R Booth
• 金额: $ 7.33万
• 依托单位: NORTHWESTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8442270
• 关键词: 13 year old; Adult; Angiosperms; Behavioral; Behavioral Research; Brain; Brain region; Child; Childhood; Cognitive; Development; Education; Elements; Flowers; Functional Magnetic Resonance Imaging; Future; Goals; Human; Image Analysis; Inferior; Inferior frontal gyrus; Intelligence; Language; Language Development; Lateral; Learning; Learning Disorders; Left; Link; Mathematics; Memory; Modeling; Neural Pathways; Parietal; Parietal Lobe; Play; Prefrontal Cortex; Process; Reliance; Research; Role; Signal Transduction; Specificity; System; Testing; Tulip plant; age related; base; early adolescence; mathematics disability; mental representation; neurodevelopment; neuroimaging; neuromechanism; relating to nervous system; specific language impairment

DESCRIPTION (provided by applicant): Deductive reasoning is central to human intelligence and plays a fundamental role in the learning and understanding of fundamental concepts during childhood. Deductions also contribute significantly to mathematical and language learning. Given the central role of deductive reasoning in education, it is critical to advance our understanding of the cognitive and neural underpinnings of its development. Neuroimaging research in adults suggests that the brain regions that are engaged in deduction partially depend upon the type of task. For example, posterior parietal regions that have been linked to visuo-spatial processing have been implicated in linear relational reasoning (e.g., Tom is taller than Bill, Bill is taller than John, therefore Tom is taller than John), whereas left inferior fronal regions associated with verbal processing have been implicated in categorical reasoning (e.g., All Tulips are Flowers, All Flowers are Plants, therefore All Tulips are Plants). However, neuroimaging studies in adults also show that the left rostro-lateral prefrontal cortex is involved in both relational and categorical reasoning, suggesting a more general role for this region in the manipulation and integration of the premises of all types of reasoning problems. Although there have been several neuroimaging studies in adults and behavioral studies in children, nothing is known about the neural basis of the development of deductive reasoning in children. This project will use functional magnetic resonance imaging (fMRI) to investigate the neural development of relational and categorical reasoning in typically developing children (8-9 versus 12-13 year olds). We will examine differences in signal intensity using conventional fMRI analyses, but we will also examine differences in effective connectivity using dynamic causal modeling (DCM). The results of this project will indicate how deductive reasoning emerges and interacts with spatial and verbal systems during childhood and early adolescence. By identifying the neural development of deductive reasoning in typically developing children, our study will also provide the necessary groundwork for future studies that will investigate how this developmental trajectory differs in children with specific language impairment and dyscalculia.

描述（由申请人提供）：演绎推理是人类智力的核心，在儿童时期学习和理解基本概念方面发挥着重要作用。演绎法对数学和语言学习也有很大的帮助。鉴于演绎推理在教育中的核心作用，促进我们对其发展的认知和神经基础的理解至关重要。对成年人的神经成像研究表明，参与推理的大脑区域部分取决于任务的类型。例如，与视觉空间处理有关的后顶叶区域已经涉及线性关系推理（例如，汤姆比比尔高，比尔比约翰高，因此汤姆比约翰高），而与言语处理相关的左下额叶区域与分类推理有关（例如，所有的郁金香都是花，所有的花都是植物，因此所有的郁金香都是植物。然而，对成年人的神经影像学研究也表明， 在关系和分类推理中，这表明该区域在 操纵和整合所有类型的推理问题的前提。虽然有几个神经影像学研究在成人和儿童的行为研究，没有什么是已知的神经基础的发展演绎推理的儿童。该项目将使用功能性磁共振成像（fMRI）来研究典型发育儿童（8-9岁与12-13奥尔兹）的关系和分类推理的神经发育。我们将使用传统的fMRI分析来检查信号强度的差异，但我们也将使用动态因果模型（DCM）来检查有效连接的差异。这个项目的结果将表明演绎推理如何出现，并与空间和语言系统在童年和青春期早期的相互作用。通过识别典型发育儿童的演绎推理的神经发育，我们的研究也将为未来的研究提供必要的基础，这些研究将调查这种发展轨迹在特定语言障碍和计算障碍儿童中的差异。