CERED USF/Moffitt Transdisciplinary Center to Address Cancer Health Disparities

CERED USF/莫菲特跨学科中心致力于解决癌症健康差异问题

• 批准号: 8059116
• 负责人: B LEE GREEN
• 金额: $ 140万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-31 至 2013-07-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8059116
• 关键词: Address; Cancer Center; Caring; Communities; Decision Making; Effectiveness; Institution; Malignant neoplasm of prostate; Medical; Minority; Parents; Patients; Population; Prostate; Provider; Qualifying; Research Infrastructure; Research Personnel; Research Project Grants; Screening for Prostate Cancer; Screening procedure; Specimen; cancer care; cancer health disparity; comparative effectiveness; effectiveness research; health disparity

DESCRIPTION (provided by applicant): The USF-Moffitt Transdisciplinary Center to Address Cancer Health Disparities is submitting this revision application to support the establishment of a Center of Excellence for conducting Comparative Effectiveness Research for Eliminating Disparities (CERED). The USF Moffitt CERED will conduct a comparative effectiveness research project regarding informed decision making in prostate cancer screening. Prostate cancer represents an important cancer health disparity nationally and locally in our community. Medical organizations have uniformly called for informed, individualized decision making for prostate screening but it is unclear if this is currently taking place in usual medical care settings or whether alternative strategies would be more effective. The proposed study will yield important information to inform patients, providers, and medical organizations. In addition, the CERED will also build research infrastructure in Comparative Effectiveness Research leveraging existing strengths and current institutional efforts in this field. The revision application takes advantage of existing Center core activities to educate our community about comparative effectiveness research in health disparities and to invite their participation, and to increase the number of qualified researchers in this field. The proposed CERED research project provides an opportunity to promote accrual into studies supported by the parent P20 initiative and to provide biologic specimens to support comparative effectiveness studies targeting health disparities more broadly. The Moffitt Cancer Center has an extensive infrastructure in bio-specimen banking (Total Cancer Care(r)) and an expanding infrastructure in comparative effectiveness research. A paucity of bio-specimens from minority populations, however, limits the effectiveness of this infrastructure to address health disparities questions. The revision application activities are thus intended to strengthen the ability of the institutions to engage in meaningful comparative effectiveness research targeting health disparities.

描述(由申请人提供)：美国联邦-莫菲特癌症健康差异跨学科中心正在提交这份修订申请，以支持建立一个进行消除差异比较有效性研究的卓越中心(CERED)。USF Moffitt CERED将进行一项关于前列腺癌筛查中知情决策的比较有效性研究项目。前列腺癌代表着全国和我们社区中一个重要的癌症健康差距。医疗组织一致呼吁为前列腺癌筛查做出知情的、个性化的决策，但目前尚不清楚这是否正在常规医疗环境中进行，或者替代策略是否会更有效。这项拟议的研究将产生重要信息，以告知患者、提供者和医疗组织。此外，经济、社会和文化权利研究中心还将利用该领域的现有优势和当前的机构努力，建立比较有效性研究的研究基础设施。修订申请利用中心现有的核心活动，教育我们的社区关于健康差距的比较有效性研究，并邀请他们参与，并增加该领域的合格研究人员的数量。拟议的CERED研究项目提供了一个机会，促进将应计收入纳入由母体P20倡议支持的研究，并提供生物标本，以支持针对更广泛的健康差距的比较有效性研究。莫菲特癌症中心在生物标本库(全面癌症护理(R))方面拥有广泛的基础设施，在比较有效性研究方面也有不断扩大的基础设施。然而，来自少数群体的生物标本的缺乏限制了这一基础设施解决健康差距问题的有效性。因此，修订申请活动旨在加强各机构进行针对健康差距的有意义的比较有效性研究的能力。