Mayo Comprehensive Cancer Center Grant (MICEO Supp) - Impact of Multi-Channel Communication Campaigns on Cancer Prevention, Control and Survivorship (CaPCaS) in Black, Hispanic, and Rural Populations

梅奥综合癌症中心拨款 (MICEO Supp) - 多渠道沟通活动对黑人、西班牙裔和农村人口癌症预防、控制和生存 (CaPCaS) 的影响

• 批准号: 10889628
• 负责人: CHERYL LYNN WILLMAN
• 金额: $ 20万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10889628
• 关键词: Administrative Supplement; Adoption; Advocate; Arizona; Attitude; Awareness; Behavior; Behavioral; Black Populations; Breast; Cancer Advocacy; Cancer Center Support Grant; Cancer Death Rates; Catchment Area; Clinic; Clinical Trials; Colorectal; Colorectal Cancer; Communication; Communities; Community Health; Community Outreach; Comprehensive Cancer Center; Continuity of Patient Care; Death Rate; Education; Florida; General Population; Geography; Goals; Grant; Health; Health Educators; Health Professional; Health system; Hispanic; Hispanic Populations; Intention; Knowledge; Life Style; Lung; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Malignant neoplasm of prostate; Midwestern United States; Pancreas; Population; Prevention; Preventive; Prostate; Public Health; Research Personnel; Rural Population; Scientist; Site; Survivors; Target Populations; Training; aged; black men; cancer care; cancer health disparity; cancer prevention; community engagement; evidence base; genetic testing; handbook; health communication; health equity; implementation science; improved; innovation; literacy; mortality; programs; response; screening; survivorship

ABSTRACT This application is being submitted by the Mayo Clinic Comprehensive Cancer Center (MCCCC) in response to the “Administrative Supplements for the NCI P30 Cancer Center Support Grants for Multi-Channel Communication Campaigns”. The MCCCC community outreach and engagement activities are led by the MCCCC Community Outreach & Engagement (COE) Office and Programs in three MCCCC catchment areas (CAs), including Arizona (AZ), Florida (FL) and the Midwest/Mayo Clinic Health Systems (MCHS). Although our 3-site catchment areas (CAs) are unique communities, the top cancers at each site are lung, breast, prostate, colorectal and pancreas. However, cancer disparities are uniquely different for the priority populations. In AZ CA, the targeted cancers are colorectal cancer (CRC) and liver cancer. Hispanics are twice likely to die from liver cancer compared to NH Whites. Although the CRC mortality rate is similar for both Hispanic and NH Whites, the CRC mortality rate for AZ CA Hispanics is elevated compared to US Hispanics. In FL CA, the targeted cancer is prostate cancer (CaP) in NH Black men. CaP leads cancer mortality among NH Blacks in the FL CA. Black men are twice as likely to die from CaP. The CaP death rate for Black men in FL is also elevated compared to the death rate for US Black men. In the Midwest/MCHS CA, the targeted cancers are lung, prostate, and colorectal cancers. These cancers are three of the top five cancers in the CA. The proposed supplement project focuses on Track 2, targeting the general population aged 30 years and above. Multi-channel communication campaigns will be delivered by Community Health Educators (CHEs) across the cancer care continuum and tailored to each of the MCCCC CAs. The primary goal of the supplement is to assess the impact of multi-channel communication campaigns targeting Black, Hispanic, and Rural populations on cancer prevention, control and survivorship (CaPCaS). This goal will be achieved through three specific aims: (1) Using the MCCCC Cancer Advocacy Handbook, train 15 (5 at each site) cancer advocates/survivors to lead the CaPCaS communication campaigns as CHEs, focusing primarily on improving cancer health and clinical trials literacy, increasing awareness about cancer prevention, screenings and genetic testing, and promoting preventive lifestyle behaviors; Adapt and implement evidence-based and innovative, culturally tailored, multi-channel educational communication campaigns tailored to Black men in FL CA, Hispanics in AZ CA and rural populations in the Midwest/MCHS geographies; and Evaluate the impact of the CaPCaS campaigns relative to increasing CaPCaS-related knowledge, attitudes, behavioral intention and adoption of prevention behavior.The academic-community team assembled for this project is comprised of health equity scientists, behavioral scientists (including implementation science researchers), clinician scientists, and public health professionals with significant expertise in health communications. (2) (3)

摘要

项目成果

Epigenetic alteration contributes to the transcriptional reprogramming in T-cell prolymphocytic leukemia.

• DOI: 10.1038/s41598-021-87890-9
• 发表时间: 2021-04-15
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Tian S;Zhang H;Zhang P;Kalmbach M;Lee JH;Ordog T;Hampel PJ;Call TG;Witzig TE;Kay NE;Klee EW;Slager SL;Yan H;Ding W
• 通讯作者: Ding W

Prediagnostic alcohol consumption and colorectal cancer survival: The Colon Cancer Family Registry.

• DOI: 10.1002/cncr.30446
• 发表时间: 2017-05-15
• 期刊: Cancer
• 影响因子: 6.2
• 作者: Phipps AI;Robinson JR;Campbell PT;Win AK;Figueiredo JC;Lindor NM;Newcomb PA
• 通讯作者: Newcomb PA

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein.

• DOI: 10.1016/j.canlet.2016.05.017
• 发表时间: 2016-09-28
• 期刊: CANCER LETTERS
• 影响因子: 9.7
• 作者: Wang, Yu;Ding, Xiwei;Wang, Shaoqing;Moser, Catherine D.;Shaleh, Hassan M.;Mohamed, Essa A.;Chaiteerakij, Roongruedee;Allotey, Loretta K.;Chen, Gang;Miyabe, Katsuyuki;McNulty, Melissa S.;Ndzengue, Albert;Fritcher, Emily G. Barr;Knudson, Ryan A.;Greipp, Patricia T.;Clark, Karl J.;Torbenson, Michael S.;Kipp, Benjamin R.;Zhou, Jie;Barrett, Michael T.;Gustafson, Michael P.;Alberts, Steven R.;Borad, Mitesh J.;Roberts, Lewis R.
• 通讯作者: Roberts, Lewis R.

Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers.

• DOI: 10.1158/1055-9965.epi-16-0496
• 发表时间: 2017-03
• 期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
• 作者: Dashti SG;Buchanan DD;Jayasekara H;Ait Ouakrim D;Clendenning M;Rosty C;Winship IM;Macrae FA;Giles GG;Parry S;Casey G;Haile RW;Gallinger S;Le Marchand L;Thibodeau SN;Lindor NM;Newcomb PA;Potter JD;Baron JA;Hopper JL;Jenkins MA;Win AK
• 通讯作者: Win AK

Multi-trait genome-wide association study identifies a novel endometrial cancer risk locus that associates with testosterone levels.

• DOI: 10.1016/j.isci.2023.106590
• 发表时间: 2023-05-19
• 期刊: ISCIENCE
• 影响因子: 5.8
• 作者: Wang, Xuemin;Kho, Pik Fang;Ramachandran, Dhanya;Bafligil, Cemsel;Amant, Frederic;Goode, Ellen L.;Scott, Rodney J.;Tomlinson, Ian;Evans, D. Gareth;Crobie, Emma J.;Doerk, Thilo;Spurdle, Amanda B.;Clubb, Dylan M.;O'Mara, Tracy A.
• 通讯作者: O'Mara, Tracy A.