Child Health Career Development Program at UCSF

加州大学旧金山分校儿童健康职业发展计划

• 批准号: 8500073
• 负责人: Donna M. Ferriero
• 金额: $ 43.2万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2017-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8500073
• 关键词: Academic Training; Academy; Address; Adult; American; Arts; Asthma; Basic Science; Brain; Cardiopulmonary; Child; Child health care; Childhood; Clinical; Clinical Oncology Supplement (K12); Communicable Diseases; Communities; Congenital Heart Defects; Defect; Development; Developmental Biology; Diabetes Mellitus; Diagnosis; Discipline; Doctor of Philosophy; Environment; Faculty; Fostering; Future; Genetic; Health; Host Defense; Immunology; Institute of Medicine (U.S.); Institutes; Investments; K-Series Research Career Programs; Laboratory Research; Laboratory Scientists; Malignant Neoplasms; Medical; Medicine; Mentors; Neurobiology; Obesity; Organ; Outcome; Pediatrics; Prevention; Request for Applications; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scholarship; Science; Structure; Training; Training Programs; United States National Academy of Sciences; Ursidae Family; Vision; Work; base; career; career development; design; didactic education; experience; improved; member; next generation; pediatric department; pediatrician; programs; response; stem cell biology

DESCRIPTION (provided by applicant): This revised proposal is submitted in response to RFA-HD-13-011, Child Health Research Career Development Award (CHRCDA) Program to provide K12 awards through the CHRCDA mechanism to young pediatric investigators. The application requests resources to support four pediatricians each year who hold MD or MD/PhD degrees and have completed scholarship training in a clinical subspecialty. The rationale for the program is based on the well-documented and urgent need to support mentored career development for pediatricians to enable them to become fully independent and productive basic science researchers, and the fact that UCSF has the vision, experience and infrastructure to train the next generation of leaders in pediatric science. Our aims are to (1) offer a structured program for training academic pediatricians, (2) foster career development and promote retention of junior faculty, (3) expose promising early career pediatricians to the intellectual richness of UCSF research and (4) promote diversity in academic pediatrics. The scholars trained by this program will bring state-of-the-art approaches to bear on diagnosis, treatment and prevention of health problems in children as well as childhood onset of adult illness. The design of this program involves harnessing the expertise of world-class basic laboratory scientists who will serve as mentors for interdisciplinary training. The basic science training program is focused around seven scientific cores: cancer, cardiopulmonary medicine, developmental biology, genetics, immunology, neurobiology, and stem cell biology. Each core has a Director, designated faculty, and a specific didactic curriculum. The scholars, in conjunction with their mentor and Core Director, will also participate in a program of additional discipline-specific course work dependent on both the prior experience and training of the applicant and the scientific theme of the trainee's research, which may often overlap amongst different cores. We believe that the Department of Pediatrics at UCSF has the vision, experience, and infrastructure to train the next generation of leaders in academic pediatrics. In this application, we provide evidence that the Department together with the broader UCSF research community comprise an exceptional environment for preparing young pediatricians who will receive support through the CHRCDA mechanism for successful careers as basic science researchers. For example, there are over 1,000 research laboratories and over 2,200 active research projects at UCSF, and the faculty currently includes 4 Nobel laureates, 41 National Academy of Sciences members, 61 American Academy of Arts and Sciences members, 72 Institute of Medicine members, and 16 Investigators of the Howard Hughes Medical Institute. This program is an investment in the future of children's health, as the diverse group of researchers we will train will harness advanced research strategies to address urgent problems (e.g., asthma, cancer, infectious diseases, host defense defects, diabetes, obesity, and developmental malformations of the heart, brain, and other organs), that will result in new treatments to improve child health outcomes.

描述（由申请人提供）：本修订提案是为了响应 RFA-HD-13-011 儿童健康研究职业发展奖 (CHRCDA) 计划而提交，旨在通过 CHRCDA 机制向年轻儿科研究人员提供 K12 奖项。该申请要求每年提供资源来支持四名拥有医学博士或医学博士/博士学位并已完成临床专业奖学金培训的儿科医生。该计划的基本原理是基于有据可查且迫切需要支持儿科医生的指导性职业发展，使他们成为完全独立和富有成效的基础科学研究人员，以及加州大学旧金山分校拥有培养下一代儿科科学领导者的愿景、经验和基础设施。我们的目标是 (1) 为培训学术儿科医生提供结构化计划，(2) 促进职业发展并促进初级教师的保留，(3) 让有前途的早期职业儿科医生接触 UCSF 研究的丰富知识，(4) 促进学术儿科的多样性。该项目培训的学者将采用最先进的方法来诊断、治疗和预防儿童健康问题以及成人疾病的儿童发病。该计划的设计涉及利用世界一流基础实验室科学家的专业知识，他们将担任跨学科培训的导师。基础科学培训项目围绕七个科学核心：癌症、心肺医学、发育生物学、遗传学、免疫学、神经生物学和干细胞生物学。每个核心都有一名主任、指定的教师和特定的教学课程。学者们还将与他们的导师和核心主任一起参加一个额外的特定学科课程项目，该项目取决于申请人的先前经验和培训以及受训者研究的科学主题，这些项目通常可能在不同的核心之间重叠。我们相信，加州大学旧金山分校儿科拥有培养下一代学术儿科领导者的远见、经验和基础设施。在本申请中，我们提供的证据表明，该部门与更广泛的 UCSF 研究界一起为年轻儿科医生提供了一个特殊的环境，他们将通过 CHRCDA 机制获得支持，作为基础科学研究人员取得成功的职业生涯。例如，加州大学旧金山分校拥有超过 1,000 个研究实验室和超过 2,200 个活跃的研究项目，目前的教员包括 4 名诺贝尔奖获得者、41 名美国国家科学院院士、61 名美国艺术与科学学院院士、72 名医学研究所成员以及 16 名霍华德休斯医学研究所的研究人员。该计划是对儿童健康未来的投资，因为多元化 我们将培训的研究人员小组将利用先进的研究策略来解决紧迫的问题（例如哮喘、癌症、传染病、宿主防御缺陷、糖尿病、肥胖以及心脏、大脑和其他器官的发育畸形），从而开发出新的治疗方法来改善儿童的健康结果。