14th Annual Joint Meeting of the Great Lakes GPCR Retreat and Club des Recepteurs

申请者描述(由申请人提供)：本申请书旨在申请拨款，资助学员参加第十四届“五大湖GPCRRat”和“Club des Repteers‘Sept Domesons Transmalers du Québec”(申请书中简称“GPCRreat”)年度联席会议的报名费。GPCRRetreat专注于我们对细胞如何通过G蛋白偶联受体(GPCRs)相互通信和环境通信的理解方面的进展，G蛋白偶联受体是最大的膜蛋白类别，也是市场上当前药物的最大类别之一。这一膜蛋白家族的重要性在今年的2012年诺贝尔化学奖颁奖典礼上得到了认可。自1999年第一次GPCR务虚会以来，该活动已从一个地方性会议发展成为一个国际公认的会议，吸引了来自美国、加拿大和世界各地的研究人员。GPCR务虚会将首次由凯斯西部储备大学赞助，并将于2013年10月17日至19日在俄亥俄州克利夫兰举行。会议的人数上限为200人，会议地点的选择是为了确保学生、博士后和学术界和工业界的主要研究人员能够讨论和辩论GPCR研究的最新发现。会议的一个主要重点是学员的参与。从历史上看，受训人员约占参会人员的三分之二。为了最大限度地促进受训人员的参与，这群年轻科学家通常会获得注册费补贴。本申请书请求提供资金，以便继续为受训人员提供这种补贴。PHS 398/2590(06/09版)页面续格式页面

DESCRIPTION (provided by applicant): The present application is a request for funds to subsidize the registration costs for trainees to attend the 14th Annual Joint Meeting of the "Great Lakes GPCR Retreat" and "Club des R¿cepteurs ¿ Sept Domains Transmembranaires du Qu¿bec" (referred to as "GPCR Retreat" in the application). The GPCR Retreat focuses on advances in our understanding of how cells communicate with each other and the environment via G protein-coupled receptors (GPCRs), the largest class of membrane proteins and one of the largest classes of current drugs on the market. The importance of this family of membrane proteins was recognized this year by the awarding of the 2012 Nobel Prize in Chemistry. Since the first GPCR Retreat in 1999, the event has grown from a local meeting into an internationally recognized conference attracting researchers from the United States, Canada, and around the world. For the first time, the GPCR Retreat will be sponsored by Case Western Reserve University and will be hosted in Cleveland, OH from October 17th-19th, 2013. The meeting is capped at 200 participants and the venue chosen to ensure an intimate atmosphere for students, postdocs, and principle investigators in academia and industry to discuss and debate the most recent findings in GPCR research. A major emphasis of the meeting is on participation by trainees. Historically, trainees represent about 2/3 of the attendees. To promote maximal participation by trainees, registration fees are typically subsidized for this group of young scientists. The present application is a request for funds to continue this subsidization for trainees. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page