The Molecular Biology and Genotyping Core

摘要 分子生物学和基因分型核心 分子生物学和基因分型核心的目标是提高个人的能力， 实验室进行视觉科学研究，需要对小鼠模型进行基因分型，并使用其他 分子生物学方法。因此，本单元的具体目标如下：1）提供一个 集中定位和支持小鼠基因分型; 2）培训研究人员并提供单独的实验室 协助他们的分子生物学项目;和3）提供培训和获得共享的核心 分子生物学和其他设备。该核心由经验丰富的人员运行， VSRC研究人员有效地管理他们的小鼠群体，降低小鼠饲养成本，检测和 消除不需要的突变，增加小鼠模型在研究中的实用性，并最终使其 科学更具成本效益和生物相关性。节省时间和资源的服务 生物学和基因分型核心是非常有价值的视觉研究人员在案件。

ABSTRACT The Molecular Biology and Genotyping Core The objective of the Molecular Biology and Genotyping Core is to enhance the capabilities of individual laboratories in conducting vision science research that requires genotyping of mouse models and use of other molecular biology methods. Accordingly, the Specific Aims of this Module are as follows: 1) to provide a centralized location and support for mouse genotyping; 2) to train researchers and provide individual laboratories with assistance in their molecular biology projects; and 3) to provide training and access to shared in the Core molecular biology and other equipment. The availability of this Core, run by highly experienced personnel, helps VSRC investigators to efficiently manage their mouse colonies, reduce the cost of mouse housing, detect and eliminate undesired mutations, increase the utility of mouse models in their research, and ultimately make their science more cost-efficient and biologically relevant. Time- and resource-saving services of the Molecular Biology and Genotyping Core are of great value to vision researchers at Case.