FASEB SRC on Epigenetics, Chromatin & Transcription

FASEB SRC 表观遗传学、染色质

• 批准号: 8525736
• 负责人: RAMIN SHIEKHATTAR
• 金额: $ 0.5万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-15 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8525736
• 关键词: Address; Aging; Area; Bahamas; Biology; Cells; Chromatin; Chromatin Structure; Collaborations; DNA Packaging; DNA Sequence; Development; Developmental Biology; Discipline; Disease; Environmental Exposure; Epigenetic Process; Fostering; Functional RNA; Funding; Gene Expression; Gene Expression Regulation; Genetic Transcription; Genome; Genomics; Goals; Heritability; Inherited; International; Lead; Malignant Neoplasms; Molecular Profiling; Organism; Postdoctoral Fellow; Predisposition; Process; Proteins; Reading; Research; Research Personnel; Scientist; Signal Transduction; Specificity; Stem cells; System; Therapeutic Intervention; abstracting; cell type; cohort; environment related cancer; fundamental research; interest; medical specialties; meetings; novel; protein expression; public health relevance; response; symposium

DESCRIPTION (provided by applicant): This application seeks partial funding for a FASEB Summer Conference on "Epigenetics Chromatin & Transcription", to be held June 16-21, 2013 in Nassau, Bahamas. The major goal of this conference is provide a forum to bring together several disciplines addressing the epigenetic changes that occur across the genome in response to signals (developmental and environmental) and in disease. This meeting will provide a much needed venue for researchers whose interests converge on these important questions, so that they can review key developments in this growing field, and to foster and inspire new research directions. Importantly, epigenetic research encompasses a wide diversity of specialties, ranging from those studying the fundamental biology underlying epigenetic inheritance to those focusing on the influences of intra- and extra-cellular signals. This meeting is unique in endeavoring to bring together these multiple aspects. From its inception in 1991, this FASEB conference has regularly attracted a strong international group of attendees and speakers, and, indeed, is one of the most consistently successful FASEB meetings. Moreover, to reflect this dynamic field, the focus of the meeting continually evolves. This year, we are emphasizing genomic approaches to understanding how transient signals can lead to persistent chromatin regulatory states in both the normal development of an organism and in disease. In addition, to expand the interest area, we have included a new cohort of speakers focusing on non-coding RNAs and their influence on chromatin and epigenetic features of the genome. Finally, we plan to markedly diversify the speaker group by selecting 8-12 additional speakers, especially promising post-doctoral scientists, from abstracts. The specific objectives of the meeting are: 1.To provide a comprehensive and critical review of the field of epigenetic regulation of gene expression. The meeting extends from basic biology of epigenetic heritability into other key areas, such as genomic and systems approaches, non-coding RNAs, windows of susceptibility (e.g. developmental biology and the use of stem cells), as well as disease areas (e.g. environmental exposures and cancer). 2. To advance cutting-edge research in this expanding field, through presentation and lively discussion of novel breakthroughs. 3. To bring together senior and junior scientists of all ranks, encouraging wide- ranging discussions and promoting the development of young scientists.

描述（由申请人提供）：本申请将为2013年6月16日至21日在巴哈马拿骚举行的关于“表观遗传学染色质和转录”的FaseB夏季会议的部分资金。这次会议的主要目标是提供一个论坛，以汇集几个学科，以解决基因组中对信号（发育和环境）以及疾病中发生的表观遗传变化。这次会议将为研究人员提供一个急需的场所，他们的兴趣在这些重要问题上汇聚在一起，以便他们可以回顾这个不断发展的领域的关键发展，并促进和激发新的研究指示。重要的是，表观遗传学研究包括各种各样的专业，从研究基础生物学的表观遗传遗传的基本生物学到关注细胞内和细胞外信号的影响的人。这次会议在努力将这些多个方面汇总在一起时是独一无二的。从1991年的成立开始，这次FASEB会议定期吸引了一个强大的国际参与者和演讲者，实际上是最成功的FASEB会议之一。此外，为了反映这一动态领域，会议的重点不断发展。今年，我们正在强调基因组方法，以了解瞬态信号如何在生物体和疾病的正常发育中导致持续的染色质调节状态。此外，为了扩大兴趣区域，我们还包括了一个专注于非编码RNA及其对基因组染色质和表观特征的影响的新的扬声器。最后，我们计划通过从摘要中选择8-12个演讲者，尤其是有希望的博士后科学家，从而显着使演讲者群体多样化。会议的具体目标是：1。对基因表达的表观遗传调节领域进行全面而批判性的审查。会议从表观遗传性遗传力的基本生物学扩展到其他关键领域，例如基因组和系统方法，非编码RNA，易感性窗口（例如发育生物学和使用干细胞的使用）以及疾病区域（例如，环境暴露和癌症）。 2。通过介绍和生动讨论新的突破，以推进这一不断扩展的领域的尖端研究。 3。将各个等级的高级科学家汇集在一起​​，鼓励广泛的讨论并促进年轻科学家的发展。