2013 Neural Crest & Cranial Placodes Gordon Research Conference

2013 神经嵴

• 批准号: 8594021
• 负责人: David W Raible
• 金额: $ 1.4万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-20 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8594021
• 关键词: Adult; Anniversary; Area; Basic Science; Biological Models; Biomedical Research; Cells; Cephalic; Childhood Solid Neoplasm; Collaborations; Communities; Congenital Abnormality; Congenital Disorders; Country; Defect; Development; Embryonic Development; Embryonic Structures; Event; Evolution; Fostering; Genome; Goals; Growth; Human; International; Light; Malignant Neoplasms; Mentors; Neoplasm Metastasis; Neural Crest; Neural Crest Cell; Oral; Population; Recording of previous events; Recruitment Activity; Regenerative Medicine; Regulation; Research; Research Personnel; Scientist; Series; Sister; Stem cells; Structure; System; Systems Biology; Time; Vertebrates; abstracting; cell motility; cell type; insight; interest; meetings; melanoma; migratory population; neoplastic cell; public health relevance; stem cell biology; symposium; technological innovation

DESCRIPTION (provided by applicant): Neural crest and cranial placodal cells make extensive contributions to embryonic structures, and are of central importance to understanding many congenital disorders. Neural crest-derived cells persist as stem cells into adulthood, and their study has provided broad insights into stem cell biology. They are a highly migratory population of cells during embryogenesis, understanding the regulation of their motility may also shed light on the misregulated invasiveness of metastatic tumor cells. The study of the neural crest and placodes has a rich history, and has been constantly growing, so it is somewhat surprising that to date there has not been a standing meeting dedicated to this topic. This conference will facilitate shared insights and fuel advances in our understanding of two developmentally, evolutionarily, and clinically important populations of cells. The ultimate goal o the conference will be to accelerate the exchange of information across different model systems, and to promote technological innovations and a genome scale understanding of the mechanisms that govern the formation, and subsequent differentiation, of the neural crest and cranial placodes.

描述（由申请人提供）：神经rest和颅骨斑块细胞对胚胎结构做出了广泛的贡献，并且对于理解许多先天性疾病至关重要。神经rest衍生的细胞持续存在，因为干细胞成年，他们的研究为干细胞生物学提供了广泛的见解。它们是胚胎发生过程中高度迁移的细胞种群，了解其运动性的调节也可能揭示转移性肿瘤细胞的侵入性不正常。对神经rest和placodes的研究具有丰富的历史，并且一直在增长，因此，到目前为止，还没有致力于该主题的会议，这是令人惊讶的。这次会议将促进我们对两个开发，进化和临床上重要的细胞种群的理解时共享的见解和燃料进步。会议的最终目标是加快跨不同模型系统的信息交换，并促进技术创新以及对控制神经rest和颅骨位置的形成和随后区分的机制的基因组规模的理解。