2013 Matrix Metalloproteinase Gordon Research Conference and Gordon Research Semi

Gordon研究会议（GRC）关于基质金属蛋白酶（MMPs） （MMP-GRC）是科学领域的首要会议，对癌症，转移性疾病，结缔组织疾病（如关节炎）以及许多炎症，肺部，心血管和神经系统疾病具有特殊的重要性。会议涵盖了与疾病相关的金属蛋白酶的所有基础和转化研究，这些酶具有共同的催化和调节机制，即MMP， ADAM（一种崩解素和金属蛋白酶），ADAMTS（带有血栓反应蛋白基序的ADAM）和astacin样蛋白酶及其抑制剂。2013年MMP-GRC将于2013年5月19日至24日在意大利托斯卡纳巴尔加的Il Ciocco Tuscany度假村举行，并与2013年5月18日至19日举行的Gordon-Kenan研究研讨会（MMP-GRS）相结合。2013年的MMP-GRC和MMP-GRS是住宅会议，这一传统一直导致了以前的MMP-GRC的成功。MMP-GRC和MMP-GRS提供了一个无与伦比的论坛，学员与既定的调查人员进行交流。会议的住宿形式促进了来自世界各地学术界、制药业和政府部门的与会科学家之间的密切互动、合作和社区意识。MMP- GRC和MMP- grs的使命是通过自由交流思想来推进科学创新，促进合作，培养该领域的下一代科学家，最终目标是促进人类健康。2013 MMP-GRC和MMP-GRS主要关注癌症，并创新地强调金属蛋白酶作为分子网络和疾病途径的组成部分。会议包括9个会议，强调未发表数据的展示，并提供充足的讨论时间，并提供额外的空闲时间进行非正式互动。会议由经验丰富的科学家主持，他们来自金属蛋白酶界，因为他们在该领域的专业知识，多样性和地位。演讲者的国际名单实现了性别平衡和具有代表性的民族/种族多样性，并包括许多早期职业研究者。通过确保大多数受邀演讲者以前没有在MMP-GRC上发言，强调社区更新。会议计划同样强调基础科学和转化科学。每个基础课程都与理解癌症途径高度相关，并且有一个额外的强烈强调细胞外基质，它不仅与癌症基质有关，而且与结缔组织疾病有关。参与者是根据他们对该领域相关的兴趣和当前活动以及提交的正在进行的工作摘要来选择的。第三个

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Matrix Metalloproteinases (MMPs) (the MMP-GRC) is the premier meeting in a scientific field of exceptional importance for cancer, metastatic disease, connective tissue disorders such as arthritis, and numerous inflammatory, lung, cardiovascular and neurological conditions. The conference spans the full spectrum of fundamental and translational research on disease-relevant metalloproteinases that share catalytic and regulatory mechanisms, i.e., MMP, ADAM (a disintegrin and metalloproteinase), ADAMTS (ADAM with thrombospondin motifs) and astacin-like proteases, and their inhibitors. The 2013 MMP-GRC will be held at the Il Ciocco Tuscany Resort, Barga, Tuscany, Italy, from May 19-24, 2013 and is conjoined with a Gordon-Kenan Research Seminar (MMP-GRS) (May 18-19, 2013). The 2013 MMP-GRC and MMP-GRS are residential conferences, a tradition that has consistently led to the success of previous MMP-GRCs. The MMP-GRC and MMP-GRS provide an unparalleled forum for intermingling of trainees with established investigators. The residential format of the conference promotes close interactions, collaborations, and a sense of community in the participating scientists, who are drawn from academia, pharmaceutical industry and government sectors from around the world. The mission of the MMP- GRC and MMP-GRS is to advance scientific innovation with free exchange of ideas, to facilitate collaborations, and to nurture the next generation of scientists i the field, all with the ultimate goal of promoting human health. The 2013 MMP-GRC and MMP-GRS have a major disease focus on cancer, and an innovative thematic emphasis on metalloproteinases as integral components of molecular networks and disease pathways. The conference comprises 9 sessions that emphasize presentation of unpublished data and offer abundant time for discussion, with additional free time available for informal interactions. Sessions are chaired by experienced scientists, who are drawn from within the metalloproteinase community for their expertise, diversity and stature in the field. The international slate of speakers achieves a gender balance and representative cross-section of ethnic/racial diversity and includes numerous early-career investigators. Community renewal is emphasized by ensuring that the majority of invited speakers have not spoken before at a MMP-GRC. The conference program gives equal emphasis to fundamental and translational science. Each fundamental session is highly relevant to understanding cancer pathways, and there is an additional strong emphasis on extracellular matrix, which is relevant not only to cancer stroma, but also to connective tissue disease. Participants are selected based on their interest in and current activities relevant to the field, and on submitted abstracts of their ongoing work. A third of the conference platform presentations will be selected from the abstracts with two poster sessions allowing abundant time for discussion. We expect the conference to stimulate and inspire, and to set new goals and directions for cutting-edge research for the near future.