Collaborative Research on Learning and Decision Making in Patients with Major Dep
专业患者学习与决策的合作研究
基本信息
- 批准号:8410857
- 负责人:
- 金额:$ 15.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-09-18 至 2014-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAntidepressive AgentsAreaBasal GangliaBrainBrain DiseasesCharacteristicsClinicalClinical TreatmentCognitionCognitiveCollaborationsComputersConsanguinityDataDatabasesDecision MakingDevelopmentDiagnosisDiseaseDoctor of MedicineDoctor of PhilosophyEducationEnvironmentFacultyFamilyFemaleFundingFutureGrantGrowthHealth Services ResearchHippocampus (Brain)HumanHuman ResourcesIncidenceInstitutesInternationalJointsJournalsLeadLearningMajor Depressive DisorderMediatingMedicalMedical centerMental HealthMiddle EastMoodsNeurologyNeuronsNeurosciencesNeurosciences ResearchNew JerseyNew TerritoriesPalestinianPaperPatientsPeer ReviewPharmaceutical PreparationsPilot ProjectsPredispositionPreparationPsychiatristPsychiatryPublishingPunishmentRecruitment ActivityResearchResearch InfrastructureResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingRewardsRodentScienceSelective Serotonin Reuptake InhibitorStudentsTestingTimeTrainingUnited States National Institutes of HealthUniversitiesVideoconferencesVideoconferencingWest BankWomanbasebrain researchcognitive functionearly onsetexperiencefollow-upfollower of religion Jewishmedical schoolsmenneurogenesisnorth shore long islandnovelpatient populationprogramsresponse
项目摘要
DESCRIPTION (provided by applicant): This proposal is a collaboration between Rutgers University-Newark (New Jersey, USA) and the Al-Quds University (Abu Dis, West Bank/Palestinian Territories) to support research, education, and infrastructural development for "Collaborative Research on Learning and Decision Making in Patients with Major Depressive Disorder." Focusing on Major Depressive Disorder (MDD) targets a critical local mental health issue and provides a rare opportunity to take advantage of the many unique cultural, environmental, familial, and clinical aspects of MDD among West Bank Palestinians with implications for advancing the science and clinical treatment of MDD worldwide. In 2008 the Rutgers/Al-Quds Brain Research Exchange was established by the P.I. (Mark Gluck, Ph.D., of Rutgers) and our lead Palestinian collaborator, Adel Misk, M.D. (faculty, Al-Quds), along with Mohammad Herzallah, M.D. (a Palestinian medical doctor, now a doctoral candidate at Rutgers), and Yasin Tayem, M.D., Ph.D. (faculty, Al-Quds); for more information see http://neuroscience.med.alquds.edu and http://www.alquds.rutgers.edu. The current exchange program provides the framework within which the scientific, educational, and infrastructural programs proposed here will lead, ultimately, to the establishment of a future Palestinian Neurosciences Institute at Al-Quds University. With this R21 grant, the investigators will (1) further develop the environment, personnel, and infrastructure at Al-Quds University for neuroscience research, (2) study the cognitive correlates of Major Depressive Disorder among West Bank Palestinians, focusing on how the disease and antidepressant medications alter learning and decision making, and (3) use the collected data and expected infrastructural growth as the basis for a future R01 proposal to the NIH Brain Disorders in the Developing World program. Although the current research focus will be on MDD, the infrastructure created, and the Palestinian faculty and students to be trained, will likely expand to address many other mental health and brain research issues in coming years. This will create at Al-Quds University in Abu Dis, West Bank, a regional powerhouse in neuroscience, neurology, and psychiatry research and training. Based in the West Bank/Palestinian Territories, these new programs will be a formidable contributor to research and health care in the West Bank, as well as a viable research and educational partner for collaborative relationships worldwide and in the Middle East.
PUBLIC HEALTH RELEVANCE: In our proposed project, we will focus on studying the cognitive correlates of Major Depressive Disorder (MDD) and antidepressant administration among West Bank Palestinians, where MDD is the #1 mental health problem, affecting approximately 24% of men and 45% of women, a rate two to three times higher than in the USA. Our project will support further development of the environment, personnel, and infrastructure at Al-Quds University for neuroscience research, as well as target a critical local mental health issue in the West Bank and take advantage of unique cultural, environmental, familial, and clinical aspects of MDD among Palestinians to answer important questions about this disorder and advance the science and clinical treatment of MDD worldwide.
描述(由申请人提供):这项提议是罗格斯大学纽瓦克分校(美国新泽西州)和圣城大学(阿布迪斯,约旦河西岸/巴勒斯坦领土)之间的合作,旨在支持研究、教育和基础设施发展,以“关于重度抑郁症患者学习和决策的合作研究”。关注严重抑郁障碍(MDD)针对的是一个严重的当地精神健康问题,并提供了一个难得的机会,可以利用约旦河西岸巴勒斯坦人中MDD的许多独特的文化、环境、家庭和临床方面的影响,并对促进全世界MDD的科学和临床治疗产生影响。2008年,罗格斯/圣城脑研究交流中心由罗格斯大学的P.I.(马克·格鲁克博士)和我们的主要巴勒斯坦合作者阿德尔·米斯克医学博士(教员)、穆罕默德·赫扎拉医学博士(巴勒斯坦医学博士,现为罗格斯大学博士生)和牙生·泰姆医学博士(教职圣城博士)共同建立;欲了解更多信息,请访问http://neuroscience.med.alquds.edu和http://www.alquds.rutgers.edu.目前的交流计划提供了一个框架,在这个框架内,这里提出的科学、教育和基础设施计划将最终导致在圣城大学建立一个未来的巴勒斯坦神经科学研究所。有了这笔R21拨款,研究人员将(1)进一步发展圣城大学用于神经科学研究的环境、人员和基础设施,(2)研究约旦河西岸巴勒斯坦人中严重抑郁障碍的认知相关性,重点研究疾病和抗抑郁药物如何改变学习和决策,以及(3)使用收集的数据和预期的基础设施增长作为未来R01提案的基础,NIH大脑障碍在发展中世界计划。尽管目前的研究重点将是MDD,但创建的基础设施以及将接受培训的巴勒斯坦教职员工和学生可能会在未来几年扩大到解决许多其他心理健康和大脑研究问题。这将在约旦河西岸阿布迪斯的圣城大学创建一个神经科学、神经学和精神病学研究和培训的地区强国。总部设在西岸/巴勒斯坦领土的这些新方案将对西岸的研究和医疗保健做出巨大贡献,并成为全球和中东合作关系的可行研究和教育伙伴。
公共卫生相关性:在我们提议的项目中,我们将重点研究约旦河西岸巴勒斯坦人中严重抑郁障碍(MDD)和抗抑郁药物治疗的认知相关性,在约旦河西岸,MDD是头号精神健康问题,影响大约24%的男性和45%的女性,这一比例比美国高出两到三倍。我们的项目将支持圣城大学神经科学研究的环境、人员和基础设施的进一步发展,并针对约旦河西岸一个关键的当地精神健康问题,利用巴勒斯坦人MDD独特的文化、环境、家庭和临床方面的优势,回答有关这种疾病的重要问题,并在世界范围内推进MDD的科学和临床治疗。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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MARK A GLUCK其他文献
MARK A GLUCK的其他文献
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{{ truncateString('MARK A GLUCK', 18)}}的其他基金
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