Individual Nutrition Therapy and Exercise Regime: A Controlled Trial of Injured, Vulnerable Elderly (INTERACTIVE trial).

个体营养治疗和运动制度：受伤、弱势老年人的对照试验（互动试验）。

• 批准号: nhmrc : 426758
• 负责人: A/Pr Craig Whitehead
• 金额: $ 38.18万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/individual-nutrition-therapy-interactive-trial/95141
• 关键词: Individual; Nutrition; Therapy; Exercise; Regime

Hip fractures are a common and growing problem for older Australians. Unfortunately recovery is incomplete in most people. In this study two factors believed to be important for recovery will be investigated - exercise and nutrition. After a hip fracture the ability to walk is severely compromised, as are appetite and dietary intake. These factors are likely to contribute to the loss of muscle mass and strength frequently observed amongst this patient group. There is considerable evidence to suggest that this loss has serious consequences in terms of ability to return to pre-injury levels of function, restriction in independence and ultimately transfer into a hostel or nursing home. Given these facts it makes sense that an exercise program incorporating strength and functional activities, and a nutrition program aimed at achieving nutritional requirements, will improve ability to walk, but there is no conclusive evidence that this is so. Only a small number of studies have tested whether an exercise program improves recovery after a hip fracture and these have mostly commenced weeks or months after the injury when it is likely that there has been irreversible decline in muscle mass and strength. In contrast, most of the nutrition studies commence soon after the injury but provide protein and calories insufficient to meet requirements, provide supplements that patients find difficult to drink or provide the supplements for only a short duration. This study will use the best quality research methods to test whether providing a 6-month individualised exercise and nutrition program to hip fracture patients soon after injury improves walking and other important health outcomes. Patients will be followed for 12 months to determine what difference the exercise and nutrition programs make. If they help then health services will have the evidence they need to recommend this type of program to the growing number of older Australians that suffer a hip fracture.

对于澳大利亚老年人来说，髋部骨折是一个普遍且日益严重的问题。不幸的是，大多数人的恢复是不完整的。在这项研究中，认为对恢复至关重要的两个因素将被研究 - 运动和营养。髋部骨折后，行走的能力将严重损害，食欲和饮食摄入量也是如此。这些因素可能导致该患者组之间经常观察到肌肉质量和力量的丧失。有大量证据表明，这种损失在恢复受伤前的职能水平，独立性限制以及最终转移到旅馆或疗养院的能力方面会产生严重的后果。鉴于这些事实是有道理的，一个锻炼计划结合了力量和功能活动，以及旨在达到营养需求的营养计划，将提高行走的能力，但没有结论性的证据证明是这样的。只有少量的研究测试了锻炼计划是否在髋部骨折后是否改善了恢复，这些锻炼大部分在受伤后几周或几个月开始，当时肌肉质量和力量可能会不可逆地下降。相比之下，大多数营养研究在受伤后不久就开始了，但提供了不足以满足需求的蛋白质和卡路里，为患者提供难以喝酒或仅在短时间内提供补充剂的补充剂。这项研究将使用最好的质量研究方法来测试是否提供6个月的个性化运动和营养计划是否在受伤后不久就可以髋部骨折患者进行髋部骨折患者，从而改善了步行和其他重要的健康状况。将遵循12个月的患者，以确定运动和营养计划的不同。如果他们提供帮助，那么卫生服务将有证据，他们需要向越来越多的遭受髋部骨折的澳大利亚老年人推荐这种计划。