CRCNS: Hybrid non-invasive brain-machine interfaces for 3D object manipulation

与物理环境交互和操纵物体是日常生活的重要组成部分。这个 上肢截肢者以及患有脊髓损伤、中风、ALS 和其他疾病的患者会丧失能力 运动障碍。这些人知道他们想做什么，也知道如果他们的手臂受伤了，他们会怎么做。 功能齐全。如果这些知识被解码并发送到假肢（或患者自己的手臂） 使用功能性电刺激器）可以恢复失去的运动功能。解码的可能性不大 完美，但是大脑可以使用实时反馈来适应不完美的解码器。几组 包括我们在内的最近已经证明，至少在原则上这是可以实现的。然而，照原样 在科学中经常出现这种情况，最初的工作是在理想化条件下完成的，并且适用于 现实世界的使用场景仍然是一个悬而未决的问题。该项目的目标是实现运动控制 脑机接口（BMI）更接近于帮助有需要的人，同时利用 我们收集的丰富数据集是为了增进我们对感觉运动控制和学习的理解。这个 将通过创建混合 BMI 来实现，该 BMI 利用多个来源的信息，并结合 来自机器学习和自动控制的现代算法。 相关性（参见说明）： 能够与物理环境交互并操纵物体是日常生活的重要组成部分。 脑机接口是让失去这种能力的患者恢复这种能力的一种方法。拟议的 该项目将使脑机接口更接近于帮助患者完成现实世界的物体操作任务。

Interacting with the physical environment and manipulating objects is an essential part of daily life. This ability is lost in upper-limb amputees as well as patients with spinal cord injury, stroke, ALS and other movement disorders. These people know what they want to do as well as how they would do it if their arms were functional. If such knowledge is decoded and sent to a prosthetic arm (or to the patient's own arm fitted with functional electric stimulators) the lost motor function could be restored. The decoding is unlikely to be perfect however the brain can adapt to an imperfect decoder using real-time feedback. Several groups including ours have recently demonstrated that at least in principle this can be achieved. However, as is often the case in science, the initial work has been done in idealized conditions and its applicability to real-world usage scenarios remains an open question. The goal of this project is to bring movement control brain-machine interfaces (BMIs) closer to helping the people who need them, and at the same time exploit the rich datasets we collect in order to advance our understanding of sensorimotor control and learning. This will be accomplished by creating hybrid BMIs which exploit information from multiple sources, combined with modern algorithms from machine learning and automatic control. RELEVANCE (See instructions): Being able to interact with the physical environment and manipulate objects is an essential part of daily life. Brain-machine interfaces are one way to restore this ability to patients who have lost it. The proposed project will bring brain-machine interfaces closer to helping patients in real-worid object manipulation tasks.