2012 Microbial Toxins & Pathogenicity Gordon Research Conference & Gordon Researc

戈登微生物毒素和致病性研究会议（GRC）是微生物发病机制领域最受重视的国际会议之一。自1972年以来，该会议每两年举行一次。2012年会议将于7月8日至13日在新罕布什尔州的沃特维尔谷度假村举行，并将与学生经营的微生物毒素和致病性戈登研究研讨会（GRS）相结合，直接在GRC之前。2012年GRC会议旨在介绍细菌毒素的分子作用、微生物病原体对宿主的操纵、病原体和宿主对先天免疫反应的控制以及正常菌群破坏在调节传染病中的作用等方面的突破性成果。演讲者包括资深的研究者，以及在该领域取得了一些最惊人发现的年轻研究者。会议包括9个专题讨论会。第一次会议将有两个主题演讲，由该领域两个最重要学科的领导者：分子发病机制和毒理学。每次会议将由一位首席研究员主持，他将对会议所涉及的研究领域进行具有挑衅性的概述。讨论领袖还将在每次演讲后的问答环节中保持与会者和演讲者之间的高水平互动。除了9个专题讨论会外，会议期间还有2个海报讨论会。鼓励每位与会者发表演讲或制作海报。GRC之前将举行戈登研究研讨会（GRS）。GRS由博士后和研究生策划和参加，在GRC主席的指导下组织。微生物毒素和致病性GRS允许研究微生物发病机制的学员之间进行科学互动。2010年的GRS有51名博士后和研究生参加，他们参加了10场演讲和2场海报会议，预计将有类似数量的参与者参加拟议的会议。两位GRS参与者还将在2010年GRC会议上介绍他们的研究。

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Microbial Toxins and Pathogenicity is one of the most highly regarded international conferences in microbial pathogenesis. The conference has met biennially since 1972. The 2012 meeting will be held from July 8-13 at the Waterville Valley Resort in New Hampshire, and will be coupled with the student-run Gordon Research Seminar (GRS) on Microbial Toxins and Pathogenicity that directly precedes the GRC. The 2012 GRC conference has been designed to allow the presentation of breakthrough results in the molecular action of bacterial toxins, host manipulation by microbial pathogens, control of innate immune responses by both the pathogen and the host, and the role of normal flora disruption in modulating infectious diseases. Speakers include established investigators as well as junior investigators who have made some of the most stunning recent discoveries in the field. The conference includes nine seminar sessions. The first session will have two keynote addresses by workers who are leaders in the two most important disciplines in this field: molecular pathogenesis and toxinology. Each session will be chaired by a leading investigator who will present a provocative overview of the area of research being covered in the session. The Discussion Leader will also serve to maintain a high level of interaction between attendees and speakers during the question and answer session after each talk. In addition to the nine seminar sessions, two poster sessions are active throughout the conference. Each attendee is encouraged to present either a talk or a poster. The GRC will be preceded by the Gordon Research Seminar (GRS). The GRS is planned and attended by postdoctoral fellows and graduate students and is organized under the guidance of the GRC chairperson. The GRS on Microbial Toxins and Pathogenicity allows scientific interactions among trainees studying microbial pathogenesis. The 2010 GRS was attended by 51 post-doctoral fellows and graduate students who participated in ten talks and two poster sessions, and a similar number of participants is expected for the proposed conference. Two GRS participants will also present their research at the 2010 GRC conference. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Microbial Toxins and Pathogenicity is a biennial meeting of the top investigators in the field of microbial pathogenesis that will be coupled with a Gordon Research Seminar for trainees. The conference has been designed to maximize exposure of both leading investigators and trainees to the most exciting new research in microbial pathogenesis, in a highly interactive environment that encourages the formation of new collaborations between individuals with diverse interests in fields associated with toxinology, microbial virulence and the innate immune response.