Phonetic influences on auditory feedback control

语音对听觉反馈控制的影响

• 批准号: 8474743
• 负责人: Caroline Niziolek
• 金额: $ 5.39万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8474743
• 关键词: Acoustics; Affect; Area; Auditory; Auditory Perception; Auditory area; Behavioral; Brain; Categories; Communication impairment; Crowding; Development; Diagnosis; Diagnostic; Disease; Feedback; Financial compensation; Functional Magnetic Resonance Imaging; Glean; Goals; Hearing; Impairment; Knowledge; Lead; Learning; Linguistics; Literature; Magnetoencephalography; Measures; Modeling; Modification; Monitor; Motor; Nature; Neighborhoods; Output; Parkinson Disease; Perception; Phonetics; Process; Production; Proprioception; Psychophysics; Research; Signal Transduction; Sorting - Cell Movement; Spastic Dysphonias; Speech; Speech Development; Speech Disorders; Staging; Structure; Stuttering; Time; Training; Variant; Visual; auditory feedback; base; design; improved; motor control; neuroimaging; novel; rehabilitation strategy; relating to nervous system; research study; response

DESCRIPTION (provided by applicant): A fundamental issue in speech research is the interaction between production and perception. The nature of this interaction has profound implications for understanding and modeling speech development, production deficits, and rehabilitation strategies. Our goal is to characterize how perception of others' speech, particularly at the phoneme boundary, influences the auditory-motor feedback processes that guide self- produced speech. On the one hand, a speaker may perceive his own speech in the categorical manner in which listeners perceive it, allowing for rapid, robust auditory processing. On the other hand, a speaker may monitor his output at a sub-categorical level, before high-level auditory cortex imposes phonetic structure on the acoustic signal. We aim to distinguish these hypotheses by examining speech under conditions of auditory change and probing the neural signal for an increased response to that change when it is phonetically relevant. Our project combines psychophysical and magnetoencephalography experiments to investigate the neural dynamics elicited by a sudden modification of speakers' auditory feedback. The proposed experiments were designed to achieve two specific aims. First, we aim to measure the neural responses to real-time phonetic category changes. Drawing on the results of past studies, we hypothesize that a cross-category or "phonetic" shift causes a greater neural response than a within-category or "non-phonetic" shift of the same magnitude, but the dynamics of this response are still unknown. The goal is to use MEG to examine the time- varying neural response to unexpected feedback perturbation, contrasting that response under conditions of phonetic and non-phonetic change. Secondly, we aim to assess the effects of speech training on auditory feedback control. Learning a novel vowel target in formant space has the effect of adding new category boundaries between the novel vowel and the well-learned native vowels. The proposed experiments evaluate the degree to which these newly-learned categories affect the responses to perturbation of an existing vowel. The proposed research adds to the existing feedback literature by introducing the distinction between meaningful linguistic changes and mere acoustic variations imposed in feedback. We aim to improve models of speech motor control by determining whether auditory feedback control is influenced by categorical perception, and therefore whether it occurs at a high or low level in auditory cortex. This research is directly applicable to stuttering, a motor control disorder thought to reflect abnormalities in feedback processing. These studies will also ultimately contribute to improved diagnosis and treatment of communication disorders such as Parkinsons' Disease or spasmodic dysphonia, since neuroimaging of feedback control can be used diagnostically to probe the specific abnormalities in brain networks involved in perception and production. Finally, the training studies proposed here could potentially be useful in developing feedback-related training strategies for a variety of speech disorders.

描述（由申请人提供）：言语研究的一个基本问题是生产和感知之间的相互作用。这种相互作用的本质对于理解和建模言语发展、表达缺陷和康复策略具有深远的影响。我们的目标是描述他人言语的感知，特别是在音素边界处，如何影响指导自我产生言语的听觉运动反馈过程。一方面，说话者可以以听众感知的分类方式感知自己的语音，从而实现快速、稳健的听觉处理。另一方面，在高级听觉皮层将语音结构强加于声学信号之前，说话者可以在子类别级别监控他的输出。我们的目标是通过检查听觉变化条件下的语音并探测神经信号以在语音相关时对该变化的反应增强来区分这些假设。 我们的项目结合了心理物理学和脑磁图实验，以研究说话者听觉反馈突然改变所引起的神经动力学。所提出的实验旨在实现两个特定目标。首先，我们的目标是测量对实时语音类别变化的神经反应。根据过去的研究结果，我们假设跨类别或“语音”转变会比相同幅度的类别内或“非语音”转变引起更大的神经反应，但这种反应的动态仍然未知。目标是使用 MEG 检查对意外反馈扰动的时变神经反应，对比语音和非语音变化条件下的反应。其次，我们的目的是评估言语训练对听觉反馈控制的影响。在共振峰空间中学习新元音目标具有在新元音和充分学习的本地元音之间添加新类别边界的效果。所提出的实验评估了这些新学习的类别对现有元音扰动响应的影响程度。 拟议的研究通过引入有意义的语言变化和反馈中施加的纯粹声学变化之间的区别，对现有的反馈文献进行了补充。我们的目标是通过确定听觉反馈控制是否受到钙类别感知的影响，以及它是否发生在听觉皮层的高水平或低水平来改进言语运动控制模型。这项研究直接适用于口吃，这是一种运动控制障碍，被认为反映了反馈处理的异常。这些研究最终还将有助于改善帕金森病或痉挛性发声障碍等沟通障碍的诊断和治疗，因为反馈控制的神经成像可用于诊断性地探测涉及感知和生产的大脑网络中的特定异常。最后，这里提出的训练研究可能有助于针对各种言语障碍制定与反馈相关的训练策略。