早期大脑发育和儿童肥胖-猫眼课题宝

早期大脑发育和儿童肥胖

批准号：

10413825

负责人：

Susan Carnell

金额：

$52.67万

依托单位：

RHODE ISLAND HOSPITAL

依托单位国家：

美国

项目类别：

财政年份：

2020

资助国家：

美国

项目状态：

已结题

起止时间：

2020-06-01 至 2024-05-31

来源：

https://reporter.nih.gov/project-details/10413825

关键词：

6 year old Address Adolescent obesity Adult Affect Behavior Behavioral Brain Brain imaging Breast Feeding Characteristics Child Child Development Childhood Cognitive Collection Cues Data Desire for food Development Dietary intake Eating Behavior Economics Environment Environmental Risk Factor Epidemiology Food Genetic Genetic Predisposition to Disease Genotype Growth Home environment Impairment Individual Infant Informal Social Control Intake Intervention Knowledge Life Link Magnetic Resonance Imaging Measures Mediating Mediator Mental Health Modeling Neurologic Obesity Outcome Overweight Parents Pathway interactions Pattern Policies Prevention Process Protocols documentation Public Health Questionnaires Race Research Rewards Risk Role Sampling Statistical Models Structure System Techniques Testing Time Weight Work behavior measurement biobehavior cohort early childhood feeding healthy weight imaging study improved indexing kindergarten neuroimaging neuromechanism obese person obesity genetics obesity in children obesity risk obesogenic physical conditioning postnatal prenatal public education response risk variant sex social

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RELEVANCE TO PUBLIC HEALTH Improved understanding of the potential underlying early influences on child obesity is an important first step towards developing effective public health and educational policies. This study aims to examine the role of infant early childhood brain development as a potential mediator linking genetic and pre and post-natal environmental factors known to be associated with obesity, and child appetitive responses, appetitive-related characteristics, and child weight trajectories and outcomes for the first time. With more than one third of US children entering kindergarten currently overweight and at-risk for an array of preventable lifelong physical and metal health conditions, this work addresses a pressing social, economic, and public health concern with significant long-lasting affects.

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