2012 Cell Death Gordon Research Conference

2012细胞死亡戈登研究会议

• 批准号: 8309530
• 负责人: John M Abrams
• 金额: $ 1.4万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8309530
• 关键词: Aging; Area; Biological Process; Cancerous; Cell Death; Cells; Clinic; Clinical; Communities; Development; Disease; Etiology; Failure; Fostering; Funding; Immune System Diseases; International; Intervention; Italy; Knowledge; Lead; Malignant Neoplasms; Nerve Degeneration; Neurodegenerative Disorders; Oral; Participant; Pathogenesis; Pathologic; Pathology; Pathway interactions; Process; Regulation; Request for Proposals; Research; Research Personnel; Science; Scientist; Site; Specific qualifier value; Structure; Students; Therapeutic Intervention; Time; Work; age related; cancer therapy; carcinogenesis; disease diagnosis; frontier; improved; innovation; meetings; posters; symposium; unpublished works

DESCRIPTION (provided by applicant): Cell death is a fundamental biological process, universally required for normal development and firmly established in the etiology, pathogenesis and treatment of cancers and other age-related diseases. For example, excessive cell death is causal in neurodegenerative disorders, while a failure of cell death clearly contributes carcinogenesis. The control of cell death is also commonly exploited in the clinic to remove diseased or cancerous cells. The 2012 Gordon Research Conference on Cell Death (GRC) will explore the scientific frontiers of this field. Underlying themes will focus on newly discovered molecules, pathways and mech-an-isms that specify active forms of cell death. Prospects for improved treatment of disease through interventions that control cell death will also be heavily explored. By promoting the free exchange of state of the art, unpublished information, the 2012 GRC on Cell Death will accelerate discovery at the bench and facilitate new treatment opportunities in the clinic. PUBLIC HEALTH RELEVANCE: Many diseases are frequently associated with excessive, reduced or inappropriate cell death. The 2012 Gordon Research Conference on Cell Death will foster unencumbered scientific exchange, focusing on mechanisms that specify cell death in normal development and in various pathologies. The conference will accelerate discovery in these areas and will also advance new opportunities for therapeutic intervention in the many diseases that are caused by mis-regulated cell death, such as cancer, auto-immune diseases, neurodegeneration and other aging-related disorders.

描述（由申请人提供）：细胞死亡是一种基本的生物学过程，普遍需要正常发育，并在病因，发病机理和癌症和其他与年龄有关的疾病的病因学，发病机理和治疗中牢固确定。例如，过度细胞死亡是神经退行性疾病的因果关系，而细胞死亡的失败显然导致了致癌作用。在诊所中通常会利用细胞死亡的控制以去除患病或癌细胞。 2012年戈登细胞死亡研究会议（GRC）将探索该领域的科学前沿。潜在的主题将集中于新发现的分子，途径和机甲主义，这些分子，指定细胞死亡的主动形式。通过控制细胞死亡的干预措施改善疾病治疗的前景也将得到大量探索。通过促进艺术状态的自由交换，未发表的信息，2012年细胞死亡的GRC将在替补席上加速发现，并促进诊所的新治疗机会。 公共卫生相关性：许多疾病经常与过度，减少或不适当的细胞死亡有关。 2012年的戈登细胞死亡研究会议将促进未束缚的科学交流，重点是指定正常发育和各种病理中细胞死亡的机制。该会议将在这些领域加速发现，还将为许多由癌症，自身免疫性疾病，神经变性和其他与衰老相关的疾病引起的许多疾病的治疗干预促进新机会。