Alcohol intervention in men with HIV in Baltimore

描述（由申请人提供）：崔杨博士的长期职业目标是开发干预措施，以解决高危人群中的酒精使用和危险的艾滋病毒相关行为。迫切需要制定适合文化的干预措施，以减少男男女女性行为者（MSMW）的艾滋病毒感染，这是最近国家减少艾滋病毒感染计划中确定的高度优先人群。因此，K99/ROO的应用恰逢其时，为不断发展的艾滋病毒预防科学领域做出了贡献。

DESCRIPTION (provided by applicant): Dr. Cui Yang's long term career goal is to develop interventions to address alcohol use and risky HIV related behaviors among high-risk populations. There is an urgent need for the development of culturally-tailored intervention to reduce HIV infections among men who have sex with men and women (MSMW), a high priority population identified in the recent national plan for reducing HIV infection. This K99/ROO application is therefore uniquely timed to contribute to a growing field of HIV prevention science. Overseen by a team of mentors, Dr. Yang's training objectives include 1) To gain expertise in alcohol risk-reduction interventions, 2) To enhance knowledge of alcohol use measurement among high risk populations; and 3) To further develop skills in qualitative methods and application of advanced statistical methods. In the mentored phase research (K99), Dr. Yang will conduct both qualitative (n=40) and quantitative interviews with 40 participants recruited from Baltimore, MD to 1) explore the social factors associated with alcohol use in the context of high risk sex behaviors, 2) to examine the feasibility of peer-driven intervention, and 3) to develop reliable and valid measures of alcohol use. The training objectives and mentored phase research are instrumental to the successful advancement to the ROO phase research which proposes to develop intervention materials and will compare outcomes between two study conditions: (1) standard individual voluntary counseling and testing (VCT) (n=100), and (2) experimental condition (n=100). In the experimental condition, participants will be trained in the reduction of alcohol use and sexual risk behaviors, peer outreach, and communication skills so that they can conduct HIV prevention and alcohol reduction outreach among their risk network members. Participants in the comparison group will receive the standard care of HIV testing and counseling. All participants will be assessed at baseline and 6-month follow up. Finding of this pilot peer-driven intervention will provide significant preliminary data for an R01 grant of a prevention intervention to address issues of sexual health and alcohol-related risks among men who have HIV or at a higher risk of acquiring HIV.