Vector-borne Disease Research Training Program in China

项目摘要 中国媒介传播疾病研究培训计划 这项研究培训申请寻求资金以促进职业发展和 中国在媒介生物学研究方面的能力建设。病媒传播的疾病是一个主要的 中国的公共卫生问题和媒介生物控制是最有效的方法 用于预防登革热和疟疾。然而，值得注意的是，考虑到这些 中国的病媒生物研究能力有限，经费不足。 中国在医学昆虫学研究方面的主要空白是描述性的、非描述性的 媒介生态学的机理研究，蚊子学生知识匮乏 分类学、分子生物学和基因组学技术，以及 医学昆虫学家和病媒控制政策制定者的科学发现。这 培训计划旨在填补医学昆虫学研究中的这些主要空白 和中国的病媒生物控制。此培训应用程序的科学目标侧重于 媒介种群和群落生态学、抗药性遗传学和 疟疾和登革热病媒控制的翻译研究。我们提出了两条途径： 培训：长期培训6名博士生和4名博士后研究员 中国和十名初级科学家的短期培训和专业的媒介生物控制 工作人员，包括负责媒介传播疾病控制的政策制定者。除了……之外 获得基于实验室的分子生物学和领域的研究经验- 基于生态研究，我们每年都会组织一个核心培训课程， 重点研究生物统计和数据管理、生态学、媒介系统学、科学 研究的写作和负责任的行为。核心培训课程将向 大批观众。国际培训中精良的基础设施和能力 地点(南方医科大学中国和中国疾控中心)和美国(大学 加州大学欧文分校)特别适合拟议的培训。这次培训 该计划将为中国科学家的职业发展做出重大贡献 通过将病媒生物学的实验室和现场研究经验联系起来，通过装备 为他们提供新技术，并使他们能够开发独立或 合作研究项目。本申请中涉及的主要科学问题 是世界上常见的登革热和疟疾病媒，因此我们的研究结果 该计划预计将在#年媒介传播疾病控制中具有普遍意义 其他地区。

Project Summary Vector-borne Disease Research Training Program in China This research training application seeks funding to promote career development and capacity building in vector biology research in China. Vector-borne diseases are a major public health problem in China and vector control represents the most effective method for dengue and malaria prevention. However, it is remarkable that given these circumstances vector biology research capacity in China is limited and underfunded. Among major gaps in medical entomological research in China are descriptive, non- mechanistic studies of vector ecology, student knowledge deficiency in mosquito taxonomy, molecular biology and genomics techniques, and disconnection between scientific findings from medical entomologists and vector control policy makers. This training program is designed to fill these major gaps in medical entomology research and vector control in China. The scientific objectives of this training application focus on vector population and community ecology, insecticide resistance genetics, and translational research in malaria and dengue vector control. We propose two tracks of training: long-term training of six Ph.D. students and four postdoctoral fellows from China, and short-term training of ten junior scientists and professional vector control staff, including policy makers in charge of vector-borne disease control. In addition to obtaining research experience in both laboratory-based molecular biology and field- based ecological research, each year we will organize a core training curriculum that focuses on biostatistics and data management, ecology, vector systematics, scientific writing and responsible conduct of research. The core training curriculum will be open to a large audience. The superb infrastructure and capacity in the international training sites (Southern Medical University in China and China CDC) and in the U.S. (University of California at Irvine) are particularly suitable for the proposed training. This training program will contribute significantly to the career development of the Chinese scientists by bridging laboratory and field research experience in vector biology, by equipping them with new technologies, and by enabling them to develop independent or collaborative research projects. The main scientific issues addressed in this application are common to dengue and malaria vectors in the world, thus the findings from our program are anticipated to have general significance in vector-borne disease control in other regions.