Integrative Program in Complex Biological System (ipCBS)

复杂生物系统综合计划（ipCBS）

• 批准号: 8444452
• 负责人: JOSEPH L. DERISI
• 金额: $ 24.38万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8444452
• 关键词: complex biological systems; programs

DESCRIPTION (provided by applicant): During the past decade, we have witnessed the emergence of a new era in biology. Driven largely by advances in high-throughput technologies and computational power, biologists today can collect data and measurements on a scale and complexity level unimaginable until recently. With the new era, biology is now becoming an information and engineering science that will rely not only on the fundamental organizational principles, but also on predictive modeling. Previous efforts to attract students with diverse training backgrounds were successful, creating a multidisciplinary environment. However, the complexity of the challenges ahead will require that students integrate perspectives from different disciplines to synthesize completely new approaches, rather than working within their own silos. This process of achieving true interdisciplinary training, where the boundaries of traditional disciplines are blurred, or removed altogether, requires a new approach to graduate education. To meet this challenge, we have developed a comprehensive interdisciplinary program for training students in the understanding and engineering of complex biological systems. The Integrative Program in Complex Biological Systems (ipCBS) departs significantly from a traditional curriculum. Built on an entirely new foundation focused on the observation, modeling, and manipulation of complex biological systems, the ipCBS represents a novel approach to solve the critical sociological and linguistic problems associated with training scientists to be simultaneously conversant in the languages of biology, mathematics, physics, and engineering. RELEVANCE: The University of California at San Francisco is strictly a biomedical campus. Like all of our graduate training programs, the Integrated Program in Complex Biological Systems is dedicated to advancing health worldwide. The specific research programs of our trainees and their faculty are focused on a broad range of basic and applied biomedical science, ranging from drug discovery, cancer therapeutics, viral evolution, and infectious disease, to name just a few.

描述（由申请人提供）：在过去的十年中，我们见证了生物学新时代的出现。在高通量技术和计算能力的进步的推动下，今天的生物学家可以收集数据和测量数据，其规模和复杂程度直到最近都无法想象。随着新时代的到来，生物学正在成为一门信息和工程科学，它不仅依赖于基本的组织原则，而且还依赖于预测建模。之前吸引具有不同培训背景的学生的努力取得了成功，创造了一个多学科的环境。然而，未来挑战的复杂性将要求学生整合来自不同学科的观点，以综合全新的方法，而不是在自己的筒仓内工作。在实现真正的跨学科培训的过程中，传统学科的界限被模糊或完全消除，这需要一种新的方法来研究生教育。为了迎接这一挑战，我们开发了一个全面的跨学科课程，用于培养学生对复杂生物系统的理解和工程。复杂生物系统综合课程（ipCBS）与传统课程有很大不同。ipCBS建立在一个全新的基础上，专注于复杂生物系统的观察，建模和操纵，它代表了一种新的方法来解决与训练科学家同时精通生物学，数学，物理学和工程学语言相关的关键社会学和语言学问题。 相关性：加州大学旧金山分校弗朗西斯科是严格的生物医学校园。像我们所有的研究生培训计划，在复杂的生物系统的综合方案是致力于促进全球健康。我们的学员和他们的教师的具体研究计划集中在广泛的基础和应用生物医学科学，从药物发现，癌症治疗，病毒进化和传染病，仅举几例。