Coping With HIV/AIDS in Tanzania
坦桑尼亚应对艾滋病毒/艾滋病
基本信息
- 批准号:8534365
- 负责人:
- 金额:$ 13.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-09-06 至 2014-05-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS/HIV problemAcquired Immunodeficiency SyndromeAddressAdherenceAdultAdverse effectsAfrica South of the SaharaAftercareAgeAntiretroviral drug resistanceAnxietyAppointmentAreaBed OccupancyBeliefCD4 Lymphocyte CountCaregiversCaringCase ManagerCharacteristicsChild CareClinicClinical DataCohort StudiesCommunicable DiseasesCounselingCountryCross-Sectional StudiesDataData AnalysesData CollectionDeltastabDiagnosisDiseaseDisease ProgressionEconomic FactorsEconomicsEducationEmergency SituationEnrollmentEnsureEthnic OriginEventFundingFutureGenderHIVHIV InfectionsHIV SeropositivityHIV diagnosisHealthHealth PromotionHealth StatusHealth behaviorHealthcareHome environmentHousingHuman immunodeficiency virus testIncomeIndividualInternationalInternational AIDSInterventionInterviewKnowledgeLaboratoriesLeadLifeLife ExperienceLinkLocationMalariaMediator of activation proteinMedicalMedical centerMental DepressionMental HealthModelingMorbidity - disease rateNewly DiagnosedOrphanOutcomeParticipantPatientsPeer ReviewPersonsPharmaceutical PreparationsPhysiciansPlayPoliciesPopulation StudyPredispositionPreventionPrevention educationProtocols documentationProviderPsychosocial FactorPublic HealthQuality of lifeRecruitment ActivityRegimenReportingResearchResearch PersonnelResistanceResourcesRespondentRiskRisk BehaviorsRisk ReductionRoleRuralSamplingSelf EfficacySeriesServicesSeveritiesSexual abuseSiteSocial supportSocioeconomic StatusStigmataStressSymptomsSystemTanzaniaTestingTimeTime StudyTransportationTraumaTreatment EfficacyTreatment ProtocolsTreatment outcomeTrustTuberculosisUniversitiesViral Load resultVirusWomanWorkantiretroviral therapybasecare seekingcohortcopingcostcost effectivedemographicsdesigndiariesethnic minority populationfightinghealth care service utilizationhealth related quality of lifehigh riskhigh risk sexual behaviorimprovedinterestmedication compliancemortalitypatient populationphysical abusepillprogramspsychological distresspsychosocialresearch studyresidencescale upservice utilizationsocial stigmasymposiumtertiary caretreatment adherenceurban areaviral resistance
项目摘要
Two-thirds of the >38 million people with HIV/AIDS reside in Sub-Saharan Africa. Access to
antiretroviral therapy (ART) in less wealthy nations is expanding quickly, creating an urgent need to
understand those factors influencing adherence, a key determinant of ongoing efficacy of ART, so that
the creation and spread of medication-resistant virus is limited. The proposed research team has
identified suboptimal adherence among 29% of clinic attendees taking ART for > 6 months in Moshi
Tanzania, while documenting lack of virologic suppression in 32% and antiretroviral drug resistance
in 10%. We propose to follow 750 newly diagnosed HIV+ persons, 500 previously diagnosed HIV+
persons and 750 HIV-negative persons in over 3 years in this region. The newly diagnosed HIV+ and
HIV- cohorts will be obtained through consecutive sampling in a Voluntary Counseling and Testing
(VCT) site and the on-going HIV+ cohort will be similarly drawn from the Infectious Disease Clinic
(IDC) in the tertiary care medical center 5 miles away. This research team has a track record of
successful past and ongoing research at both the VCT and the IDC sites. Baseline data we will used
to examine associations between psychosocial (including trauma, mental health symtomotology,
coping strategies and life events), sociodemographic, and economic factors and health status,
adherence to ART, and health promotion and high risk activities. Longitudinal analyses will examine
causal relationships between changes in the independent and dependent variables. Results will lead
to the creation of more effective prevention and care models for the area and other similar areas.
Studying the population of ART naive patients in a resource poor setting provides a unique window of
opportunity to gather data designed to increase our understanding of underlying variables associated
with maladherence and risk behaviors. Psychosocial determinants are a unique strength of this
proposal. The study will result in a minimum of 7 peer reviewed articles and disemination of findings
at annual national (US and Tanzanian) and international AIDS, Public Health and Mental Health
conferences, including the annual Tanzania national AIDS conference. A policy related report will be
diseminated to national and international leaders.
3800万艾滋病毒/艾滋病患者中有三分之二居住在撒哈拉以南非洲。访问
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
KATHRYN WHETTEN其他文献
KATHRYN WHETTEN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('KATHRYN WHETTEN', 18)}}的其他基金
Secondary Analysis of Existing Alcohol & HIV/AIDS Data
对现有酒精的二次分析
- 批准号:
6892414 - 财政年份:2005
- 资助金额:
$ 13.55万 - 项目类别:
相似海外基金
RESEARCH SUPPORT SERVICES FOR THE DIVISION OF ACQUIRED IMMUNODEFICIENCY SYNDROME
获得性免疫缺陷综合症分类的研究支持服务
- 批准号:
10219039 - 财政年份:2020
- 资助金额:
$ 13.55万 - 项目类别:
RESEARCH SUPPORT SERVICES FOR THE DIVISION OF ACQUIRED IMMUNODEFICIENCY SYNDROME
获得性免疫缺陷综合症分类的研究支持服务
- 批准号:
9981476 - 财政年份:2019
- 资助金额:
$ 13.55万 - 项目类别:
IGF::OT::IGF RESEARCH SUPPORT SERVICES FOR THE DIVISION OF ACQUIRED IMMUNODEFICIENCY SYNDROME
IGF::OT::IGF 针对获得性免疫缺陷综合症分类的研究支持服务
- 批准号:
9364184 - 财政年份:2016
- 资助金额:
$ 13.55万 - 项目类别:
Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) in Saskatchewan- Where are we now and what does the future hold?
萨斯喀彻温省的人类免疫缺陷病毒(HIV)和获得性免疫缺陷综合症(艾滋病)——我们现在在哪里以及未来会怎样?
- 批准号:
236932 - 财政年份:2011
- 资助金额:
$ 13.55万 - 项目类别:
Miscellaneous Programs
ACQUIRED IMMUNODEFICIENCY SYNDROME RESEARCH REVIEW COMMI
获得性免疫缺陷综合症研究审查委员会
- 批准号:
3554155 - 财政年份:1991
- 资助金额:
$ 13.55万 - 项目类别:
ACQUIRED IMMUNODEFICIENCY SYNDROME RESEARCH REVIEW COMMI
获得性免疫缺陷综合症研究审查委员会
- 批准号:
3554156 - 财政年份:1991
- 资助金额:
$ 13.55万 - 项目类别:
ACQUIRED IMMUNODEFICIENCY SYNDROME RESEARCH REVIEW
获得性免疫缺陷综合症研究综述
- 批准号:
2063342 - 财政年份:1991
- 资助金额:
$ 13.55万 - 项目类别: