Spatiotemporal Neuroimaging of Situated Sentence Comprehension

情境句子理解的时空神经影像

• 批准号: 8277431
• 负责人: David Norman Caplan
• 金额: $ 25.49万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8277431
• 关键词: Affect; Area; Brain; Cereals; Complex; Comprehension; Data; Diagnosis; Disease; Etiology; Frequencies; Functional Magnetic Resonance Imaging; Goals; Hippocampus (Brain); Judgment; Licensing; Linguistics; Location; Magnetoencephalography; Measures; Memory; Motor; Pattern; Process; Relative (related person); Research; Resolution; Semantic memory; Signal Transduction; Source; Structure; Structure of inferior temporal gyrus; Structure of middle temporal gyrus; Testing; Time; Time Study; Visual; abstracting; base; heuristics; lexical; neuroimaging; operation; phrases; relating to nervous system; response; spatiotemporal; syntax

Project Summary/Abstract The goal of the proposed research is to characterize the location and functional interaction over time of areas of the brain involved in aspects of sentence comprehension. The research is undertaken within a framework that sees comprehension as having multiple information "sources," and as being "interactive" and "situated." This view of sentence comprehension maintains that the propositional meaning of a sentence is, in the final analysis, determined by its syntactic structure and lexical content, and, when comprehension is successful, this meaning is arrived at by a process that assigns syntactic structure (parsing) and combines it with lexical meanings to determine propositional meaning (syntactically-based interpretation, which we will refer to simply as "interpretation"). However, these integrated, central processes are not the only sources of propositional representations that are considered as candidates for the meaning of a sentence. Propositional meanings are also assigned by asyntactic processes such as heuristics that assign agent to a preverbal noun (comprehension has "multiple sources"). These multiple sources yield candidates for the meaning of a sentence on-line, which are eventually eliminated in favor of the syntactically licensed interpretation(s) of a sentence. In addition, parsing and interpretation are affected in an on-line fashion by a variety of types of information such as the frequency of lexical forms and their co-occurrence (comprehension is "interactive"), and by non- linguistic factors such as task conditions (comprehension is "situated"). The proposed research will identify areas of the brain that are involved in aspects of parsing and interpretive operations and their on-line interaction with non-linguistic processes. We will study the two major types of these interactions - those between parsing and interpretation and perceptual and motor processes and those between parsing and interpretation and semantic memory. We will use MR-constrained integrated magnetoencephalography (MEG) and electroelcephalography (EEG) to obtain measures of neural activity that have both fine-grained temporal and spatial resolution, and apply Granger causation analyses (Granger, 1969) to these data to identify patterns of directional causal influence between functionally interpretable ROIs during sentence processing.

项目总结/摘要 拟议研究的目标是表征的位置和功能的相互作用， 大脑中涉及句子理解方面的区域的时间。这项研究是 在一个将理解视为具有多种信息的框架内进行 “来源”，以及“互动”和“定位”。“这种句子理解的观点 认为一个句子的命题意义，归根结底，是由它的 句法结构和词汇内容，并且，当理解成功时，这个意义是 通过分配句法结构（分析）并将其与词汇结构相结合的过程来实现。 意义来确定命题意义（基于句法的解释，我们将 简称为“解释”）。然而，这些综合的中央进程并不是唯一的 被认为是一个命题的意义候选的命题表示的来源 句话命题的意义也是通过诸如语义学的句法过程来分配的 将施事赋予动词前名词（理解具有“多个来源”）。这些多 源产生候选的意义，一个句子在线，这是最终消除 支持句子的句法许可解释。此外，解析和 口译以在线方式受到各种类型的信息的影响， 词汇形式的频率及其共现（理解是“互动的”），并通过非 语言因素，如任务条件（理解是“情境”）。 这项拟议中的研究将确定大脑中参与分析的区域， 解释操作及其与非语言过程的在线交互。我们将研究 这些交互的两种主要类型--分析和解释之间的交互， 知觉和运动过程以及分析和解释与语义之间的过程 记忆我们将使用MR限制的脑磁图（MEG）， 脑电描记术（EEG），以获得神经活动的措施，既有细粒度的 时间和空间分辨率，并将格兰杰因果分析（格兰杰，1969）应用于这些 识别功能上可解释的ROI之间的方向性因果影响模式的数据 在句子处理过程中。