The Role of Environmental Exposures of Silica via the Lung in the Manifestation o
The Role of Environmental Exposures of Silica via the Lung in the Manifestation o
批准号:
8535332
负责人:
KELLY INMAN
金额:
$12.57万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-30 至 2013-09-29
中文摘要
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英文摘要
To dissect the pathways associated with tissue-specific fibrosis and systemic autoimmunity, the impact of the known immunomodulatory agent silica will be evaluated in autoimmune-prone mice with a genetically introduced pro-fibrotic defect (with and without Smad7 in different cell types).
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