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Liver Targeted testing study

Liver Targeted testing study
肝脏靶向检测研究
批准号：
8535329
负责人：
KELLY INMAN
金额：
$8.08万
依托单位：
INTEGRATED LABORATORY SYSTEMS, LLC
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-30 至 2013-09-29
来源：
https://reporter.nih.gov/project-details/8535329
关键词：
Biological AssayChemicalsEvaluationIn VitroLiverPathway interactionsProtocols documentationScreening procedureSerumSprague-Dawley RatsTestingToxic effectin vivoresponse

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中文摘要
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英文摘要
The proposed short-term in vivo study will provide an approach for evaluating qualitatively the concordance between the in vitro screening assays and in vivo responses in the liver and anchor pathway signatures with pathological findings. The chemicals being evaluated in this study protocol are being tested to obtain serum for analytical analysis and liver sections for histochemical and immunohistochemical evaluation.
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