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TCDD Induced Developmental Effects

TCDD Induced Developmental Effects
TCDD 诱发的发育效应
批准号：
8535330
负责人：
KELLY INMAN
金额：
$22.24万
依托单位：
INTEGRATED LABORATORY SYSTEMS, LLC
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-30 至 2013-09-29
来源：
https://reporter.nih.gov/project-details/8535330
关键词：
AddressAdultDevelopmentEstradiolExposure toFemaleGene Expression AlterationLactationMusProgesteroneRoleTetrachlorodibenzodioxinendometriosismature animalresponse

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英文摘要
The purpose of the study is to examine changes in gene expression and alteration in adult uterine responsiveness in response to developmental exposure to TCDD. The study will address the effects of developmental exposure of female mice to TCDD at GD15, lactation and/or 4 weeks, uterine responsiveness to estradiol and/or estradiol+progesterone treatment as adult animals.
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