Innate immune signalling in Mycobacterium tuberculosis infection

结核分枝杆菌感染中的先天免疫信号传导

• 批准号: nhmrc : GNT1120230
• 负责人: A/Pr Antje Blumenthal
• 金额: $ 56.29万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/innate-immune-signalling-tuberculosis-infection/1347109
• 关键词: Innate; immune; signalling; Mycobacterium; tuberculosis

Tuberculosis (TB) is a major global health threat that causes 1.5 million deaths every year. This study will characterise a new molecular control mechanism that optimises the immune response to the bacteria that cause TB and determine how it contributes to controlling the infection. Such knowledge is essential to help improve patient management and develop better treatments for this devastating disease.

结核病是一个重大的全球健康威胁，每年导致150万人死亡。这项研究将描述一种新的分子控制机制，该机制优化对导致结核病的细菌的免疫反应，并确定它如何有助于控制感染。这些知识对于帮助改善患者管理和开发这种毁灭性疾病的更好治疗方法至关重要。